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Adiponectin levels in people with Latent Autoimmune Diabetes-a case control study / Sarah, Prior; Helen, Davies; Sinead, Brophy; Jeffrey, Stephens; Mark, Atkinson

BMC Research Notes, Volume: 3, Start page: 317

Swansesa University Authors: Sarah, Prior, Helen, Davies, Helen, Davies, Sinead, Brophy, Jeffrey, Stephens, Mark, Atkinson

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DOI (Published version): 10.1186/1756-0500-3-317

Abstract

To examine adiponectin levels in people with Latent Autoimmune Diabetes in Adults using a matched pair case control study. Patients with LADA (n = 64), were matched for sex with type 2 diabetic and non-diabetic controls. A matched paired T-test was used to examine average adiponectin levels in the L...

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Published in: BMC Research Notes
Published: 2010
Online Access: http://www.biomedcentral.com/1756-0500/3/317/abstract
URI: https://cronfa.swan.ac.uk/Record/cronfa10727
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Abstract: To examine adiponectin levels in people with Latent Autoimmune Diabetes in Adults using a matched pair case control study. Patients with LADA (n = 64), were matched for sex with type 2 diabetic and non-diabetic controls. A matched paired T-test was used to examine average adiponectin levels in the LADA patients' versus controls. The average adiponectin level for the LADA patients was 9.96 μg/ml compared to 6.4 μg/ml for Type 2 matched controls and 9.6 μg/ml for non-diabetic controls. Mean difference for the LADA-type 2 comparison was calculated after data was log transformed and showed a difference of 1.58 μg/ml (95%CI: 1.28-1.95, p = 0.0001). There was no significant difference between LADA and non-diabetic controls (p = 0.54). Adiponectin levels are higher among people with LADA compared to those with type 2 diabetes and are equivalent to levels seen in non-diabetic controls. This suggests that risk of complications in LADA, as with type 1 diabetes may be related more to glycaemic control rather than to factors of the metabolic syndrome.
College: Swansea University Medical School
Start Page: 317