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Association of the adiponectin rs266729 C>G variant and coronary heart disease in the low risk ‘Golden Years’ type 1 diabetes cohort

Sarah Prior Orcid Logo, Danielle Jones, Geoffrey V. Gill, Steve C. Bain, Jeffrey Stephens Orcid Logo

Diabetes Research and Clinical Practice, Volume: 91, Issue: 3, Pages: e71 - e74

Swansea University Authors: Sarah Prior Orcid Logo, Danielle Jones, Jeffrey Stephens Orcid Logo

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Abstract

The C-allele of rs266729 is associated with CHD, while the G-allele of rs17300539 is associated with metabolic traits. We examined these in type 1 diabetes. For rs266729, the C-allele was associated with 8-fold increase in CHD. For rs17300539, the G-allele was associated with increases in triglyceri...

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Published in: Diabetes Research and Clinical Practice
ISSN: 01688227
Published: 2011
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa10731
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Abstract: The C-allele of rs266729 is associated with CHD, while the G-allele of rs17300539 is associated with metabolic traits. We examined these in type 1 diabetes. For rs266729, the C-allele was associated with 8-fold increase in CHD. For rs17300539, the G-allele was associated with increases in triglycerides and waist circumference.
Keywords: Adiponectin; Gene variant; Coronary heart disease; Obesity; Type 1 diabetes
College: Faculty of Medicine, Health and Life Sciences
Issue: 3
Start Page: e71
End Page: e74