Book chapter 663 views
Development and application of novel analytical methods in lipidomics
Yuqin Wang,
Anna Meljon,
Michael Ogundare,
William Griffiths 
Chemical Genomics and Proteomics, Second Edition
Swansea University Author:
William Griffiths
Abstract
Lipidomics can be regarded as the determination of the quantitative lipid profile of a cell type, tissue or biological fluid. Mass spectrometry has become the dominant analytical technique in lipidomics. Here we will discuss the developments in mass spectrometry-based lipidomics, highlighting method...
| Published in: | Chemical Genomics and Proteomics, Second Edition |
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| Published: |
Taylor & Francis Group
2012
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa10814 |
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| Abstract: |
Lipidomics can be regarded as the determination of the quantitative lipid profile of a cell type, tissue or biological fluid. Mass spectrometry has become the dominant analytical technique in lipidomics. Here we will discuss the developments in mass spectrometry-based lipidomics, highlighting methods based on shotgun-lipidomics, gas-chromatography - mass spectrometry and liquid-chromatography – tandem mass spectrometry. Examples will be given from the current literature and the authors own work. The importance of suitable sample preparation methods will also be emphasised. |
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| College: |
Faculty of Medicine, Health and Life Sciences |