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Stimulating somatosensory psychophysics: a double-blind, sham-controlled study of the neurobiological mechanisms of tDCS

Claire Hanley Orcid Logo, Mark Tommerdahl, David J. McGonigle

Frontiers in Cellular Neuroscience, Volume: 9

Swansea University Author: Claire Hanley Orcid Logo

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DOI (Published version): 10.3389/fncel.2015.00400

Abstract

In this study, the influence of tDCS on vibrotactile adaptation is investigated. Double-blind tDCS (Anodal/Sham) of 1 mA was delivered for 600 s to electrodes positioned in a somatosensory/contralateral orbit montage. Stimulation was applied between blocks of the implemented amplitude discrimination...

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Published in: Frontiers in Cellular Neuroscience
ISSN: 1662-5102
Published: 2015
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URI: https://cronfa.swan.ac.uk/Record/cronfa24019
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first_indexed 2015-10-29T01:58:12Z
last_indexed 2019-05-13T12:40:25Z
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spelling 2019-05-13T11:48:20.0630567 v2 24019 2015-10-28 Stimulating somatosensory psychophysics: a double-blind, sham-controlled study of the neurobiological mechanisms of tDCS 8a50e5bcfe0164091b248e4602789bd7 0000-0002-9520-8490 Claire Hanley Claire Hanley true false 2015-10-28 HPS In this study, the influence of tDCS on vibrotactile adaptation is investigated. Double-blind tDCS (Anodal/Sham) of 1 mA was delivered for 600 s to electrodes positioned in a somatosensory/contralateral orbit montage. Stimulation was applied between blocks of the implemented amplitude discrimination tasks. Amplitude discrimination thresholds were significantly degraded during adaptation trials, compared to those achieved at baseline but tDCS failed to modify task performance. Using Bayesian statistics, this finding was revealed to constitute substantial evidence for the null hypothesis. The failure of DC stimulation to alter performance is discussed in the context of several factors that may have confounded the induction of changes in cortical plasticity. Journal Article Frontiers in Cellular Neuroscience 9 1662-5102 transcranial direct current stimulation, neuromodulation, vibrotactile adaptation, amplitude discrimination, somatosensory, GABA, NMDA, Bayesian statistics 7 10 2015 2015-10-07 10.3389/fncel.2015.00400 COLLEGE NANME Psychology COLLEGE CODE HPS Swansea University 2019-05-13T11:48:20.0630567 2015-10-28T14:49:34.5399409 Faculty of Medicine, Health and Life Sciences School of Psychology Claire Hanley 0000-0002-9520-8490 1 Mark Tommerdahl 2 David J. McGonigle 3 0024019-412201630807PM.pdf Hanley_2015_tDCS.pdf 2016-04-12T15:08:07.7270000 Output 1080977 application/pdf Accepted Manuscript true 2016-05-09T00:00:00.0000000 true
title Stimulating somatosensory psychophysics: a double-blind, sham-controlled study of the neurobiological mechanisms of tDCS
spellingShingle Stimulating somatosensory psychophysics: a double-blind, sham-controlled study of the neurobiological mechanisms of tDCS
Claire Hanley
title_short Stimulating somatosensory psychophysics: a double-blind, sham-controlled study of the neurobiological mechanisms of tDCS
title_full Stimulating somatosensory psychophysics: a double-blind, sham-controlled study of the neurobiological mechanisms of tDCS
title_fullStr Stimulating somatosensory psychophysics: a double-blind, sham-controlled study of the neurobiological mechanisms of tDCS
title_full_unstemmed Stimulating somatosensory psychophysics: a double-blind, sham-controlled study of the neurobiological mechanisms of tDCS
title_sort Stimulating somatosensory psychophysics: a double-blind, sham-controlled study of the neurobiological mechanisms of tDCS
author_id_str_mv 8a50e5bcfe0164091b248e4602789bd7
author_id_fullname_str_mv 8a50e5bcfe0164091b248e4602789bd7_***_Claire Hanley
author Claire Hanley
author2 Claire Hanley
Mark Tommerdahl
David J. McGonigle
format Journal article
container_title Frontiers in Cellular Neuroscience
container_volume 9
publishDate 2015
institution Swansea University
issn 1662-5102
doi_str_mv 10.3389/fncel.2015.00400
college_str Faculty of Medicine, Health and Life Sciences
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hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str School of Psychology{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}School of Psychology
document_store_str 1
active_str 0
description In this study, the influence of tDCS on vibrotactile adaptation is investigated. Double-blind tDCS (Anodal/Sham) of 1 mA was delivered for 600 s to electrodes positioned in a somatosensory/contralateral orbit montage. Stimulation was applied between blocks of the implemented amplitude discrimination tasks. Amplitude discrimination thresholds were significantly degraded during adaptation trials, compared to those achieved at baseline but tDCS failed to modify task performance. Using Bayesian statistics, this finding was revealed to constitute substantial evidence for the null hypothesis. The failure of DC stimulation to alter performance is discussed in the context of several factors that may have confounded the induction of changes in cortical plasticity.
published_date 2015-10-07T03:28:25Z
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score 11.016235

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