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Water-structuring molecules and nanomaterials enhance radiofrequency heating in biologically relevant solutions

Nadia C. Lara, Asad A. Haider, Jason C. Ho, Lon J. Wilson, Andrew Barron Orcid Logo, Steven A. Curley, Stuart J. Corr

Chemical Communications, Volume: 52, Issue: 85, Pages: 12630 - 12633

Swansea University Author: Andrew Barron Orcid Logo

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DOI (Published version): 10.1039/C6CC06573B

Abstract

For potential applications in nano-mediated radiofrequency cancer hyperthermia, the nanomaterial under investigation must increase the heating of any aqueous solution in which it is suspended when exposed to radiofrequency electric fields. This should also be true for a broad range of solution condu...

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Published in: Chemical Communications
ISSN: 1359-7345 1364-548X
Published: 2016
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URI: https://cronfa.swan.ac.uk/Record/cronfa30918
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Abstract: For potential applications in nano-mediated radiofrequency cancer hyperthermia, the nanomaterial under investigation must increase the heating of any aqueous solution in which it is suspended when exposed to radiofrequency electric fields. This should also be true for a broad range of solution conductivities, especially those that artificially mimic the ionic environment of biological systems. Herein we demonstrate enhanced heating of biologically relevant aqueous solutions using kosmotropes and a hexamalonoserinolamide fullerene.
Item Description: This paper provides a route for cancer treatment without complex material or drugs - it shows that by the alteration of the permtivity of a solution by simple bio-safe molecules radio irradiation can be used for selective heating of tumors. This work is now moving towards animal studies.
College: Faculty of Science and Engineering
Issue: 85
Start Page: 12630
End Page: 12633

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