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Nano-analyses of wear particles from metal-on-metal and non-metal-on-metal dual modular neck hip arthroplasty

Zhidao Xia Orcid Logo, Benjamin F. Ricciardi, Zhao Liu, Christopher von Ruhland, Mike Ward, Alex Lord Orcid Logo, Louise Hughes, Steven R. Goldring, Edward Purdue, David Murray, Giorgio Perino

Nanomedicine: Nanotechnology, Biology and Medicine, Volume: 13, Issue: 3, Pages: 1205 - 1217

Swansea University Authors: Zhidao Xia Orcid Logo, Alex Lord Orcid Logo

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Abstract

Increased failure rates due to metallic wear particle-associated adverse local tissue reactions (ALTR) is a significant clinical problem in resurfacing and total hip arthroplasty. Retrieved periprosthetic tissue of 53 cases with corrosion/conventional metallic wear particles from 285 revision operat...

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Published in: Nanomedicine: Nanotechnology, Biology and Medicine
ISSN: 1549-9634
Published: Elsevier BV 2017
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URI: https://cronfa.swan.ac.uk/Record/cronfa31554
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spelling 2020-07-31T15:23:20.9802144 v2 31554 2017-01-04 Nano-analyses of wear particles from metal-on-metal and non-metal-on-metal dual modular neck hip arthroplasty c9307abfed1b43987a19da0c0e30d7a4 0000-0002-2047-7282 Zhidao Xia Zhidao Xia true false d547bad707e12f5a9f12d4fcbeea87ed 0000-0002-6258-2187 Alex Lord Alex Lord true false 2017-01-04 BMS Increased failure rates due to metallic wear particle-associated adverse local tissue reactions (ALTR) is a significant clinical problem in resurfacing and total hip arthroplasty. Retrieved periprosthetic tissue of 53 cases with corrosion/conventional metallic wear particles from 285 revision operations for ALTR was selected for nano-analyses. Three major classes of hip implants associated with ALTR, metal-on-metal hip resurfacing arthroplasty (MoM HRA) and large head total hip replacement (MoM LHTHA) and non-metal-on-metal dual modular neck total hip replacement (Non-MoM DMNTHA) were included. The size, shape, distribution, element composition, and crystal structure of the metal particles were analyzed by conventional histological examination and electron microscopy with analytic tools of 2D X-ray energy dispersive spectrometry and X-ray diffraction. Distinct differences in size, shape, and element composition of the metallic particles were detected in each implant class which correlate with the histological features of severity of ALTR and variability in implant performance. Journal Article Nanomedicine: Nanotechnology, Biology and Medicine 13 3 1205 1217 Elsevier BV 1549-9634 Hip arthroplasty; Adverse local tissue reaction (ALTR); Metal-on-metal hip resurfacing arthroplasty (MoM HRA); Metal-on-metal large head total hip replacement (MoM LHTHA); Non-metal-on-metal dual modular neck total hip replacement (non-MoM DMNTHA) 1 4 2017 2017-04-01 10.1016/j.nano.2016.11.003 COLLEGE NANME Biomedical Sciences COLLEGE CODE BMS Swansea University 2020-07-31T15:23:20.9802144 2017-01-04T10:12:56.3662493 College of Engineering Engineering Zhidao Xia 0000-0002-2047-7282 1 Benjamin F. Ricciardi 2 Zhao Liu 3 Christopher von Ruhland 4 Mike Ward 5 Alex Lord 0000-0002-6258-2187 6 Louise Hughes 7 Steven R. Goldring 8 Edward Purdue 9 David Murray 10 Giorgio Perino 11 0031554-30042019152348.pdf 31554.pdf 2019-04-30T15:23:48.1970000 Output 3032638 application/pdf Version of Record true Released under the terms of a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC-BY-NC-ND). true eng https://creativecommons.org/licenses/by-nc-nd/4.0/
title Nano-analyses of wear particles from metal-on-metal and non-metal-on-metal dual modular neck hip arthroplasty
spellingShingle Nano-analyses of wear particles from metal-on-metal and non-metal-on-metal dual modular neck hip arthroplasty
Zhidao, Xia
Alex, Lord
title_short Nano-analyses of wear particles from metal-on-metal and non-metal-on-metal dual modular neck hip arthroplasty
title_full Nano-analyses of wear particles from metal-on-metal and non-metal-on-metal dual modular neck hip arthroplasty
title_fullStr Nano-analyses of wear particles from metal-on-metal and non-metal-on-metal dual modular neck hip arthroplasty
title_full_unstemmed Nano-analyses of wear particles from metal-on-metal and non-metal-on-metal dual modular neck hip arthroplasty
title_sort Nano-analyses of wear particles from metal-on-metal and non-metal-on-metal dual modular neck hip arthroplasty
author_id_str_mv c9307abfed1b43987a19da0c0e30d7a4
d547bad707e12f5a9f12d4fcbeea87ed
author_id_fullname_str_mv c9307abfed1b43987a19da0c0e30d7a4_***_Zhidao, Xia_***_0000-0002-2047-7282
d547bad707e12f5a9f12d4fcbeea87ed_***_Alex, Lord_***_0000-0002-6258-2187
author Zhidao, Xia
Alex, Lord
author2 Zhidao Xia
Benjamin F. Ricciardi
Zhao Liu
Christopher von Ruhland
Mike Ward
Alex Lord
Louise Hughes
Steven R. Goldring
Edward Purdue
David Murray
Giorgio Perino
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container_volume 13
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container_start_page 1205
publishDate 2017
institution Swansea University
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publisher Elsevier BV
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description Increased failure rates due to metallic wear particle-associated adverse local tissue reactions (ALTR) is a significant clinical problem in resurfacing and total hip arthroplasty. Retrieved periprosthetic tissue of 53 cases with corrosion/conventional metallic wear particles from 285 revision operations for ALTR was selected for nano-analyses. Three major classes of hip implants associated with ALTR, metal-on-metal hip resurfacing arthroplasty (MoM HRA) and large head total hip replacement (MoM LHTHA) and non-metal-on-metal dual modular neck total hip replacement (Non-MoM DMNTHA) were included. The size, shape, distribution, element composition, and crystal structure of the metal particles were analyzed by conventional histological examination and electron microscopy with analytic tools of 2D X-ray energy dispersive spectrometry and X-ray diffraction. Distinct differences in size, shape, and element composition of the metallic particles were detected in each implant class which correlate with the histological features of severity of ALTR and variability in implant performance.
published_date 2017-04-01T03:50:32Z
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