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Atomic force microscopy studies of bioprocess engineering surfaces - imaging, interactions and mechanical properties mediating bacterial adhesion / Sean A. James, Nidal Hilal, Chris J. Wright, Christopher Wright

Biotechnology Journal, Start page: 1600698

Swansea University Authors: Nidal Hilal, Christopher Wright

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DOI (Published version): 10.1002/biot.201600698

Abstract

The detrimental effect of bacterial biofilms on process engineering surfaces is well documented. Thus, interest in the early stages of bacterial biofilm formation; in particular bacterial adhesion and the production of anti-fouling coatings has grown exponentially as a field. During this time, Atomi...

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Published in: Biotechnology Journal
ISSN: 1860-6768
Published: 2017
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URI: https://cronfa.swan.ac.uk/Record/cronfa32940
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Abstract: The detrimental effect of bacterial biofilms on process engineering surfaces is well documented. Thus, interest in the early stages of bacterial biofilm formation; in particular bacterial adhesion and the production of anti-fouling coatings has grown exponentially as a field. During this time, Atomic force microscopy (AFM) has become an essential tool for the evaluation of bacterial adhesion. Due to its versatility AFM offers not only insight into the topographical landscape and mechanical properties of the engineering surfaces, but elucidates, through direct quantification the topographical and biomechnical properties of the foulants The aim of this paper is to collate the current research on bacterial adhesion, both theoretical and practical, and outline how AFM as a technique is uniquely equipped to provide further insight into the nanoscale world at the bioprocess engineering surface.
Keywords: Atomic force microscopy; Bacteria; Biofouling; Force measurement; Nanoindentation
College: College of Engineering
Start Page: 1600698