Journal article 984 views
Aptamer-based biosensors for the rapid visual detection of flu viruses
T. T. Le,
B. Adamiak,
D. J. Benton,
C. J. Johnson,
Sanjiv Sharma ,
R. Fenton,
J. W. McCauley,
M. Iqbal,
A. E. G. Cass
Chem. Commun., Volume: 50, Issue: 98, Pages: 15533 - 15536
Swansea University Author: Sanjiv Sharma
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DOI (Published version): 10.1039/C4CC07888H
Abstract
RNA aptamers showing affinity and specificity for different strains of human influenza virus were assembled onto gold nanoparticles that subsequently formed a gold nanoshell (AuNS) around the viral envelope. These shells could be visualised by transmission electron microscopy (TEM). Changes in size...
Published in: | Chem. Commun. |
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ISSN: | 1359-7345 1364-548X |
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2014
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URI: | https://cronfa.swan.ac.uk/Record/cronfa36440 |
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2020-07-01T16:23:38.4328603 v2 36440 2017-11-01 Aptamer-based biosensors for the rapid visual detection of flu viruses b6b7506358522f607b171ec9c94757b7 0000-0003-3828-737X Sanjiv Sharma Sanjiv Sharma true false 2017-11-01 MEDE RNA aptamers showing affinity and specificity for different strains of human influenza virus were assembled onto gold nanoparticles that subsequently formed a gold nanoshell (AuNS) around the viral envelope. These shells could be visualised by transmission electron microscopy (TEM). Changes in size and structure of the AuNS coated virus can be used to detect the viruses. We show that sedimentation with a low cost centrifuge and visual determination can detect 3 × 108 viral particles. Journal Article Chem. Commun. 50 98 15533 15536 1359-7345 1364-548X 31 12 2014 2014-12-31 10.1039/C4CC07888H http://pubs.rsc.org/-/content/articlelanding/2014/cc/c4cc07888h/unauth#!divAbstract COLLEGE NANME Biomedical Engineering COLLEGE CODE MEDE Swansea University 2020-07-01T16:23:38.4328603 2017-11-01T16:25:09.0785996 T. T. Le 1 B. Adamiak 2 D. J. Benton 3 C. J. Johnson 4 Sanjiv Sharma 0000-0003-3828-737X 5 R. Fenton 6 J. W. McCauley 7 M. Iqbal 8 A. E. G. Cass 9 |
title |
Aptamer-based biosensors for the rapid visual detection of flu viruses |
spellingShingle |
Aptamer-based biosensors for the rapid visual detection of flu viruses Sanjiv Sharma |
title_short |
Aptamer-based biosensors for the rapid visual detection of flu viruses |
title_full |
Aptamer-based biosensors for the rapid visual detection of flu viruses |
title_fullStr |
Aptamer-based biosensors for the rapid visual detection of flu viruses |
title_full_unstemmed |
Aptamer-based biosensors for the rapid visual detection of flu viruses |
title_sort |
Aptamer-based biosensors for the rapid visual detection of flu viruses |
author_id_str_mv |
b6b7506358522f607b171ec9c94757b7 |
author_id_fullname_str_mv |
b6b7506358522f607b171ec9c94757b7_***_Sanjiv Sharma |
author |
Sanjiv Sharma |
author2 |
T. T. Le B. Adamiak D. J. Benton C. J. Johnson Sanjiv Sharma R. Fenton J. W. McCauley M. Iqbal A. E. G. Cass |
format |
Journal article |
container_title |
Chem. Commun. |
container_volume |
50 |
container_issue |
98 |
container_start_page |
15533 |
publishDate |
2014 |
institution |
Swansea University |
issn |
1359-7345 1364-548X |
doi_str_mv |
10.1039/C4CC07888H |
url |
http://pubs.rsc.org/-/content/articlelanding/2014/cc/c4cc07888h/unauth#!divAbstract |
document_store_str |
0 |
active_str |
0 |
description |
RNA aptamers showing affinity and specificity for different strains of human influenza virus were assembled onto gold nanoparticles that subsequently formed a gold nanoshell (AuNS) around the viral envelope. These shells could be visualised by transmission electron microscopy (TEM). Changes in size and structure of the AuNS coated virus can be used to detect the viruses. We show that sedimentation with a low cost centrifuge and visual determination can detect 3 × 108 viral particles. |
published_date |
2014-12-31T03:45:35Z |
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1763752159621414912 |
score |
11.016235 |