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Analysis of polar herbicides and steroids by LC-MS using atmospheric pressure ionisation techniques. / Edward R Browne

Swansea University Author: Edward R Browne

Abstract

Chapter one is a brief introduction to solid phase extraction, chromatography and mass spectrometry. A further explanation of the ionisation processes and the interfaces used to allow for coupling of high performance liquid chromatography (HPLC) to mass spectrometry (MS) is provided. The basis of ch...

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Published: 2003
Institution: Swansea University
Degree level: Doctoral
Degree name: Ph.D
URI: https://cronfa.swan.ac.uk/Record/cronfa42418
first_indexed 2018-08-02T18:54:39Z
last_indexed 2018-08-03T10:10:06Z
id cronfa42418
recordtype RisThesis
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spelling 2018-08-02T16:24:29.1817940 v2 42418 2018-08-02 Analysis of polar herbicides and steroids by LC-MS using atmospheric pressure ionisation techniques. 2d00dc3b8c9f13ab965f132a65483459 NULL Edward R Browne Edward R Browne true true 2018-08-02 Chapter one is a brief introduction to solid phase extraction, chromatography and mass spectrometry. A further explanation of the ionisation processes and the interfaces used to allow for coupling of high performance liquid chromatography (HPLC) to mass spectrometry (MS) is provided. The basis of chapter two is the separation and analysis of polar herbicides. HPLC-MS was used to perform analysis of triazine, phenylurea and acidic herbicides. Solid phase extraction was investigated for the analysis of these herbicides in river water and analysis of real samples was conducted. Chapter three involves analysis of free and conjugated estrogen steroids. The analysis of river water extracts spiked with four conjugated estrogen steroids was performed. And solid phase extraction was investigated for the analysis of free and conjugated estrogen steroids in river water and analysis of real river water samples conducted. The development of a method foe the determination of conjugated steroids in male equine urine with HPLC-MS forms the basis of chapter four. The analysis of urine samples taken before and after administration of an anabolic steroid were investigated. E-Thesis Analytical chemistry. 31 12 2003 2003-12-31 COLLEGE NANME Chemistry COLLEGE CODE Swansea University Doctoral Ph.D 2018-08-02T16:24:29.1817940 2018-08-02T16:24:29.1817940 Faculty of Science and Engineering School of Engineering and Applied Sciences - Chemistry Edward R Browne NULL 1 0042418-02082018162452.pdf 10798126.pdf 2018-08-02T16:24:52.8470000 Output 35360802 application/pdf E-Thesis true 2018-08-02T16:24:52.8470000 false
title Analysis of polar herbicides and steroids by LC-MS using atmospheric pressure ionisation techniques.
spellingShingle Analysis of polar herbicides and steroids by LC-MS using atmospheric pressure ionisation techniques.
Edward R Browne
title_short Analysis of polar herbicides and steroids by LC-MS using atmospheric pressure ionisation techniques.
title_full Analysis of polar herbicides and steroids by LC-MS using atmospheric pressure ionisation techniques.
title_fullStr Analysis of polar herbicides and steroids by LC-MS using atmospheric pressure ionisation techniques.
title_full_unstemmed Analysis of polar herbicides and steroids by LC-MS using atmospheric pressure ionisation techniques.
title_sort Analysis of polar herbicides and steroids by LC-MS using atmospheric pressure ionisation techniques.
author_id_str_mv 2d00dc3b8c9f13ab965f132a65483459
author_id_fullname_str_mv 2d00dc3b8c9f13ab965f132a65483459_***_Edward R Browne
author Edward R Browne
author2 Edward R Browne
format E-Thesis
publishDate 2003
institution Swansea University
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Engineering and Applied Sciences - Chemistry{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Chemistry
document_store_str 1
active_str 0
description Chapter one is a brief introduction to solid phase extraction, chromatography and mass spectrometry. A further explanation of the ionisation processes and the interfaces used to allow for coupling of high performance liquid chromatography (HPLC) to mass spectrometry (MS) is provided. The basis of chapter two is the separation and analysis of polar herbicides. HPLC-MS was used to perform analysis of triazine, phenylurea and acidic herbicides. Solid phase extraction was investigated for the analysis of these herbicides in river water and analysis of real samples was conducted. Chapter three involves analysis of free and conjugated estrogen steroids. The analysis of river water extracts spiked with four conjugated estrogen steroids was performed. And solid phase extraction was investigated for the analysis of free and conjugated estrogen steroids in river water and analysis of real river water samples conducted. The development of a method foe the determination of conjugated steroids in male equine urine with HPLC-MS forms the basis of chapter four. The analysis of urine samples taken before and after administration of an anabolic steroid were investigated.
published_date 2003-12-31T04:23:39Z
_version_ 1851365596116025344
score 11.089572

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