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Sub-ppm level high energy resolution fluorescence detected X-ray absorption spectroscopy of selenium in articular cartilage / Steve, Conlan; Lewis, Francis; Ilyas, Khan

The Analyst, Volume: 144, Issue: 11, Pages: 3488 - 3493

Swansea University Authors: Steve, Conlan, Lewis, Francis, Ilyas, Khan

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DOI (Published version): 10.1039/c9an00207c

Abstract

The speciation of highly-diluted elements by X-ray absorption spectroscopy in a diverse range of materials is extremely challenging, especially in biological matrices such as articular cartilage. Here we show that using a high energy resolution fluorescence detected X-ray absorption spectroscopy (HE...

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Published in: The Analyst
ISSN: 0003-2654 1364-5528
Published: Royal Society of Chemistry (RSC) 2019
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URI: https://cronfa.swan.ac.uk/Record/cronfa49778
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Abstract: The speciation of highly-diluted elements by X-ray absorption spectroscopy in a diverse range of materials is extremely challenging, especially in biological matrices such as articular cartilage. Here we show that using a high energy resolution fluorescence detected X-ray absorption spectroscopy (HERFD-XAS) technique coupled to an array of crystal analyzers, selenium speciation down to 400 ppb (μg kg-1) within articular cartilage can be demonstrated. This is a major advance in the speciation of highly-diluted elements through X-ray absorption spectroscopy and opens new possibilities to study the metabolic role of selenium and other elements in biological samples.
Issue: 11
Start Page: 3488
End Page: 3493