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Sub-ppm level high energy resolution fluorescence detected X-ray absorption spectroscopy of selenium in articular cartilage

C. Bissardon, O. Proux, S. Bureau, E. Suess, L. H. E. Winkel, Steve Conlan Orcid Logo, Lewis Francis Orcid Logo, Ilyas Khan Orcid Logo, L. Charlet, J. L. Hazemann, S. Bohic

The Analyst, Volume: 144, Issue: 11, Pages: 3488 - 3493

Swansea University Authors: Steve Conlan Orcid Logo, Lewis Francis Orcid Logo, Ilyas Khan Orcid Logo

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DOI (Published version): 10.1039/c9an00207c

Abstract

The speciation of highly-diluted elements by X-ray absorption spectroscopy in a diverse range of materials is extremely challenging, especially in biological matrices such as articular cartilage. Here we show that using a high energy resolution fluorescence detected X-ray absorption spectroscopy (HE...

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Published in: The Analyst
ISSN: 0003-2654 1364-5528
Published: Royal Society of Chemistry (RSC) 2019
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URI: https://cronfa.swan.ac.uk/Record/cronfa49778
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Abstract: The speciation of highly-diluted elements by X-ray absorption spectroscopy in a diverse range of materials is extremely challenging, especially in biological matrices such as articular cartilage. Here we show that using a high energy resolution fluorescence detected X-ray absorption spectroscopy (HERFD-XAS) technique coupled to an array of crystal analyzers, selenium speciation down to 400 ppb (μg kg-1) within articular cartilage can be demonstrated. This is a major advance in the speciation of highly-diluted elements through X-ray absorption spectroscopy and opens new possibilities to study the metabolic role of selenium and other elements in biological samples.
Issue: 11
Start Page: 3488
End Page: 3493