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Health sequelae of human cryptosporidiosis—a 12-month prospective follow-up study / B. L. Carter; R. E. Stiff; K. Elwin; H. A. Hutchings; B. W. Mason; A. P. Davies; R. M. Chalmers; Hayley Hutchings; Angharad Davies

European Journal of Clinical Microbiology & Infectious Diseases

Swansea University Authors: Hayley, Hutchings, Angharad, Davies

Abstract

A prospective cohort study of all patients with laboratory-confirmed, genotyped cryptosporidiosis in Wales, aged 6 months -45 years of age was carried out over a two year period. 205/515 cases participated, a 40% response rate. At 12 months, bewteen a fifth and a third of cases reported persistent a...

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Published in: European Journal of Clinical Microbiology & Infectious Diseases
ISSN: 0934-9723 1435-4373
Published: 2019
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa50656
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Abstract: A prospective cohort study of all patients with laboratory-confirmed, genotyped cryptosporidiosis in Wales, aged 6 months -45 years of age was carried out over a two year period. 205/515 cases participated, a 40% response rate. At 12 months, bewteen a fifth and a third of cases reported persistent abdominal pain and diarrhea, joint pain and/or fatigue. The number reporting symptoms after C. hominis infection was statistically significantly greater compared with C. parvum. Post-infectious gastrointestinal dysfunction were common after cryptosporidiosis and around 10% of people merited a formal diagnosis of IBS following cryptosporidiosis.
Keywords: cryptosporidiosis, sequelae, Cryptosporidium hominis, Cryptosporidium parvum, irritable bowel syndrome
College: Swansea University Medical School