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Health sequelae of human cryptosporidiosis—a 12-month prospective follow-up study

B. L. Carter, R. E. Stiff, K. Elwin, H. A. Hutchings, B. W. Mason, A. P. Davies, R. M. Chalmers, Hayley Hutchings Orcid Logo, Angharad Davies Orcid Logo

European Journal of Clinical Microbiology & Infectious Diseases

Swansea University Authors: Hayley Hutchings Orcid Logo, Angharad Davies Orcid Logo

Abstract

A prospective cohort study of all patients with laboratory-confirmed, genotyped cryptosporidiosis in Wales, aged 6 months -45 years of age was carried out over a two year period. 205/515 cases participated, a 40% response rate. At 12 months, bewteen a fifth and a third of cases reported persistent a...

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Published in: European Journal of Clinical Microbiology & Infectious Diseases
ISSN: 0934-9723 1435-4373
Published: 2019
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa50656
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Abstract: A prospective cohort study of all patients with laboratory-confirmed, genotyped cryptosporidiosis in Wales, aged 6 months -45 years of age was carried out over a two year period. 205/515 cases participated, a 40% response rate. At 12 months, bewteen a fifth and a third of cases reported persistent abdominal pain and diarrhea, joint pain and/or fatigue. The number reporting symptoms after C. hominis infection was statistically significantly greater compared with C. parvum. Post-infectious gastrointestinal dysfunction were common after cryptosporidiosis and around 10% of people merited a formal diagnosis of IBS following cryptosporidiosis.
Keywords: cryptosporidiosis, sequelae, Cryptosporidium hominis, Cryptosporidium parvum, irritable bowel syndrome
College: Swansea University Medical School