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Benchmark Dose Analysis of DNA Damage Biomarker Responses Provides Compound Potency and Adverse Outcome Pathway Information for the Topoisomerase II Inhibitor Class of Compounds

Ryan P. Wheeldon, Derek T. Bernacki, Stephen D. Dertinger, Steven M. Bryce, Jeffrey C. Bemis, George Johnson Orcid Logo

Environmental and Molecular Mutagenesis, Volume: 61, Issue: 4, Pages: 396 - 407

Swansea University Author: George Johnson Orcid Logo

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DOI (Published version): 10.1002/em.22360

Published in: Environmental and Molecular Mutagenesis
ISSN: 0893-6692 1098-2280
Published: Wiley 2020
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Keywords: genotoxicity; doseresponse; quantitative; mode ofaction; adverse outcomepathway
Issue: 4
Start Page: 396
End Page: 407