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Cationic Fluorene-Based Conjugated Polyelectrolytes Induce Compaction and Bridging in DNA

Matthew Davies Orcid Logo, Hugh D Burrows, Shuying Cheng, M. Carmen Morán, Maria da Graça Miguel, Peter Douglas Orcid Logo

Biomacromolecules, Volume: 10, Issue: 11, Pages: 2987 - 2997

Swansea University Authors: Matthew Davies Orcid Logo, Peter Douglas Orcid Logo

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DOI (Published version): 10.1021/bm9004996

Published in: Biomacromolecules
ISSN: 1525-7797 1526-4602
Published: 2009
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Item Description: Association between polymer and DNA is a critical feature in the use of conjugated fluorescent polyelectrolytes as biosensors, and self-assembly is a key process in structural templating in nanotechnology. In this paper, arising from an international collaboration between Swansea and the Chemistry Department in Coimbra, we report the first observation, and quantitative study, of novel compaction structures arising from interaction between DNA and conjugated fluorescent polyelectrolytes.
College: Faculty of Science and Engineering
Issue: 11
Start Page: 2987
End Page: 2997