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Mycosis Is a Disease State Encountered Rarely in Shore Crabs, Carcinus maenas

Charlotte Davies Orcid Logo, Sophie Malkin, Jessica Thomas, Frederico Batista, Andrew Rowley, Christopher Coates

Pathogens, Volume: 9, Issue: 6, Start page: 462

Swansea University Authors: Charlotte Davies Orcid Logo, Sophie Malkin, Jessica Thomas, Frederico Batista, Andrew Rowley, Christopher Coates

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DOI (Published version): 10.3390/pathogens9060462

Abstract

There is a paucity of knowledge regarding the diversity and impact(s) of disease-causing fungi in marine animals, especially shellfish. In efforts to address this knowledge gap for the shore crab Carcinus maenas, a year-long disease screen was carried out across two sites in Swansea Bay (Wales, UK)...

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Published in: Pathogens
ISSN: 2076-0817
Published: MDPI AG 2020
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URI: https://cronfa.swan.ac.uk/Record/cronfa54422
first_indexed 2020-06-10T13:08:29Z
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In efforts to address this knowledge gap for the shore crab Carcinus maenas, a year-long disease screen was carried out across two sites in Swansea Bay (Wales, UK) with a view to characterising putative fungal infections. Crabs were sampled between November 2017 and October 2018, and screened systematically for disease signatures using haemolymph (blood) preparations, targeted PCR and tissue histopathology. Strikingly, mycosis was confirmed in ~0.4% of total crabs tested (n = 1191) and restricted to one location only (Mumbles Pier). Clinical infections were observed in four out of four infected crabs. In these animals, the gills and hepatopancreas were congested with fungal morphotypes. In addition, some evidence indicates haemocyte (immune cell) reactivity toward the fungi. 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spelling 2025-04-07T13:42:00.7392936 v2 54422 2020-06-10 Mycosis Is a Disease State Encountered Rarely in Shore Crabs, Carcinus maenas a0febe211e502356dad1dab51a43761c 0000-0002-5853-1934 Charlotte Davies Charlotte Davies true false 17ff4136248e9382802ced1bc1d680e4 Sophie Malkin Sophie Malkin true false 7989695d9a7bf8989a23e253204ac50b Jessica Thomas Jessica Thomas true false 77657489849b520529e56265f39a5724 Frederico Batista Frederico Batista true false e98124f6e62b9592786899d7059e3a79 Andrew Rowley Andrew Rowley true false af160934b75bea5b8ba83d68b3d1a003 Christopher Coates Christopher Coates true false 2020-06-10 BGPS There is a paucity of knowledge regarding the diversity and impact(s) of disease-causing fungi in marine animals, especially shellfish. In efforts to address this knowledge gap for the shore crab Carcinus maenas, a year-long disease screen was carried out across two sites in Swansea Bay (Wales, UK) with a view to characterising putative fungal infections. Crabs were sampled between November 2017 and October 2018, and screened systematically for disease signatures using haemolymph (blood) preparations, targeted PCR and tissue histopathology. Strikingly, mycosis was confirmed in ~0.4% of total crabs tested (n = 1191) and restricted to one location only (Mumbles Pier). Clinical infections were observed in four out of four infected crabs. In these animals, the gills and hepatopancreas were congested with fungal morphotypes. In addition, some evidence indicates haemocyte (immune cell) reactivity toward the fungi. Phylogenetic placement of the partial internal transcribed spacer (ITS1) gene regions amplified from three mycotic crabs revealed the causative agent to be related to hypocrealean fungi, thereby representing a novel species. Journal Article Pathogens 9 6 462 MDPI AG 2076-0817 marine fungi; phylogeny; histopathology; parasite; disease connectivity; fisheries 11 6 2020 2020-06-11 10.3390/pathogens9060462 COLLEGE NANME Biosciences Geography and Physics School COLLEGE CODE BGPS Swansea University Not Required Operations were part-funded by the European Regional Development fund through the Ireland Wales Cooperation Programme, BLUEFISH, awarded to CJC and AFR. 2025-04-07T13:42:00.7392936 2020-06-10T08:48:43.9720168 Faculty of Science and Engineering School of Biosciences, Geography and Physics - Biosciences Charlotte Davies 0000-0002-5853-1934 1 Sophie Malkin 2 Jessica Thomas 3 Frederico Batista 4 Andrew Rowley 5 Christopher Coates 6 54422__17478__0442303e7f364294b7e032f77c3f5a28.pdf Davies et al_2020_Pathogens.pdf 2020-06-11T14:28:08.1637871 Output 3809208 application/pdf Version of Record true This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited true https://creativecommons.org/licenses/by/4.0/
title Mycosis Is a Disease State Encountered Rarely in Shore Crabs, Carcinus maenas
spellingShingle Mycosis Is a Disease State Encountered Rarely in Shore Crabs, Carcinus maenas
Charlotte Davies
Sophie Malkin
Jessica Thomas
Frederico Batista
Andrew Rowley
Christopher Coates
title_short Mycosis Is a Disease State Encountered Rarely in Shore Crabs, Carcinus maenas
title_full Mycosis Is a Disease State Encountered Rarely in Shore Crabs, Carcinus maenas
title_fullStr Mycosis Is a Disease State Encountered Rarely in Shore Crabs, Carcinus maenas
title_full_unstemmed Mycosis Is a Disease State Encountered Rarely in Shore Crabs, Carcinus maenas
title_sort Mycosis Is a Disease State Encountered Rarely in Shore Crabs, Carcinus maenas
author_id_str_mv a0febe211e502356dad1dab51a43761c
17ff4136248e9382802ced1bc1d680e4
7989695d9a7bf8989a23e253204ac50b
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e98124f6e62b9592786899d7059e3a79
af160934b75bea5b8ba83d68b3d1a003
author_id_fullname_str_mv a0febe211e502356dad1dab51a43761c_***_Charlotte Davies
17ff4136248e9382802ced1bc1d680e4_***_Sophie Malkin
7989695d9a7bf8989a23e253204ac50b_***_Jessica Thomas
77657489849b520529e56265f39a5724_***_Frederico Batista
e98124f6e62b9592786899d7059e3a79_***_Andrew Rowley
af160934b75bea5b8ba83d68b3d1a003_***_Christopher Coates
author Charlotte Davies
Sophie Malkin
Jessica Thomas
Frederico Batista
Andrew Rowley
Christopher Coates
author2 Charlotte Davies
Sophie Malkin
Jessica Thomas
Frederico Batista
Andrew Rowley
Christopher Coates
format Journal article
container_title Pathogens
container_volume 9
container_issue 6
container_start_page 462
publishDate 2020
institution Swansea University
issn 2076-0817
doi_str_mv 10.3390/pathogens9060462
publisher MDPI AG
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Biosciences, Geography and Physics - Biosciences{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Biosciences, Geography and Physics - Biosciences
document_store_str 1
active_str 0
description There is a paucity of knowledge regarding the diversity and impact(s) of disease-causing fungi in marine animals, especially shellfish. In efforts to address this knowledge gap for the shore crab Carcinus maenas, a year-long disease screen was carried out across two sites in Swansea Bay (Wales, UK) with a view to characterising putative fungal infections. Crabs were sampled between November 2017 and October 2018, and screened systematically for disease signatures using haemolymph (blood) preparations, targeted PCR and tissue histopathology. Strikingly, mycosis was confirmed in ~0.4% of total crabs tested (n = 1191) and restricted to one location only (Mumbles Pier). Clinical infections were observed in four out of four infected crabs. In these animals, the gills and hepatopancreas were congested with fungal morphotypes. In addition, some evidence indicates haemocyte (immune cell) reactivity toward the fungi. Phylogenetic placement of the partial internal transcribed spacer (ITS1) gene regions amplified from three mycotic crabs revealed the causative agent to be related to hypocrealean fungi, thereby representing a novel species.
published_date 2020-06-11T07:44:30Z
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