Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action

Chapman, Katherine; Wilde, Eleanor; Chapman, Fiona M.; Verma, Jatin; Shah, Ume-kulsoom; Stannard, Leanne; Seager, Anna; Tonkin, James; Brown, Rowan; Doherty, Ann T.; Johnson, George; Doak, Shareen; Jenkins, Gareth

doi:10.1007/s00204-020-02902-3

Journal article 863 views 129 downloads

Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action

Katherine Chapman

, Eleanor Wilde, Fiona M. Chapman, Jatin Verma, Ume-kulsoom Shah

, Leanne Stannard, Anna Seager

, James Tonkin, Rowan Brown

, Ann T. Doherty, George Johnson, Shareen Doak

, Gareth Jenkins

Archives of Toxicology, Volume: 95, Issue: 1, Pages: 321 - 336

Swansea University Authors: Katherine Chapman , Eleanor Wilde, Jatin Verma, Ume-kulsoom Shah , Leanne Stannard, Anna Seager , James Tonkin, Rowan Brown , George Johnson, Shareen Doak , Gareth Jenkins

PDF | Version of Record

© 2020 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution 4.0 (CC BY) License
Download (1.03MB)

Check full text

DOI (Published version): 10.1007/s00204-020-02902-3

Published in:	Archives of Toxicology
ISSN:	0340-5761 1432-0738
Published:	Springer Science and Business Media LLC 2021
Online Access:	Check full text
URI:	https://cronfa.swan.ac.uk/Record/cronfa55186
Tags:	Add Tag No Tags, Be the first to tag this record!

first_indexed	2020-10-07T15:42:41Z
last_indexed	2021-02-10T04:18:21Z
id	cronfa55186
recordtype	SURis
fullrecord	<?xml version="1.0"?><rfc1807><datestamp>2021-02-09T16:01:59.1440104</datestamp><bib-version>v2</bib-version><id>55186</id><entry>2020-09-16</entry><title>Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action</title><swanseaauthors><author><sid>19e7d85eec17117858d867ec0c9f575e</sid><ORCID>0000-0001-6668-0705</ORCID><firstname>Katherine</firstname><surname>Chapman</surname><name>Katherine Chapman</name><active>true</active><ethesisStudent>false</ethesisStudent></author><author><sid>664c7183e97777f8215222d0f5c8831d</sid><firstname>Eleanor</firstname><surname>Wilde</surname><name>Eleanor Wilde</name><active>true</active><ethesisStudent>false</ethesisStudent></author><author><sid>6c11cec3815148d928211f6648a6dce9</sid><firstname>Jatin</firstname><surname>Verma</surname><name>Jatin Verma</name><active>true</active><ethesisStudent>false</ethesisStudent></author><author><sid>bcef4e069220a4b85f8a2c0cc3059487</sid><ORCID>0000-0002-0594-580X</ORCID><firstname>Ume-kulsoom</firstname><surname>Shah</surname><name>Ume-kulsoom Shah</name><active>true</active><ethesisStudent>false</ethesisStudent></author><author><sid>4a21f43a6d275fb4908405b05e60dc5f</sid><firstname>Leanne</firstname><surname>Stannard</surname><name>Leanne Stannard</name><active>true</active><ethesisStudent>false</ethesisStudent></author><author><sid>bc76a4c997d4384daa4cc1a52a27ed64</sid><ORCID>0000-0001-8926-5504</ORCID><firstname>Anna</firstname><surname>Seager</surname><name>Anna Seager</name><active>true</active><ethesisStudent>false</ethesisStudent></author><author><sid>b6421e6d425db934fbe521640605b010</sid><ORCID/><firstname>James</firstname><surname>Tonkin</surname><name>James Tonkin</name><active>true</active><ethesisStudent>false</ethesisStudent></author><author><sid>d7db8d42c476dfa69c15ce06d29bd863</sid><ORCID>0000-0003-3628-2524</ORCID><firstname>Rowan</firstname><surname>Brown</surname><name>Rowan Brown</name><active>true</active><ethesisStudent>false</ethesisStudent></author><author><sid>97544e9483ec5a71957b53dd2c87a6d9</sid><firstname>George</firstname><surname>Johnson</surname><name>George Johnson</name><active>true</active><ethesisStudent>false</ethesisStudent></author><author><sid>8f70286908f67238a527a98cbf66d387</sid><ORCID>0000-0002-6753-1987</ORCID><firstname>Shareen</firstname><surname>Doak</surname><name>Shareen Doak</name><active>true</active><ethesisStudent>false</ethesisStudent></author><author><sid>a44095d26187304e903da7ca778697b6</sid><ORCID>0000-0002-5437-8389</ORCID><firstname>Gareth</firstname><surname>Jenkins</surname><name>Gareth Jenkins</name><active>true</active><ethesisStudent>false</ethesisStudent></author></swanseaauthors><date>2020-09-16</date><deptcode>BMS</deptcode><abstract/><type>Journal Article</type><journal>Archives of Toxicology</journal><volume>95</volume><journalNumber>1</journalNumber><paginationStart>321</paginationStart><paginationEnd>336</paginationEnd><publisher>Springer Science and Business Media LLC</publisher><placeOfPublication/><isbnPrint/><isbnElectronic/><issnPrint>0340-5761</issnPrint><issnElectronic>1432-0738</issnElectronic><keywords>In vitro; Carcinogenicity testing; Genotoxicity; Multiple endpoints</keywords><publishedDay>1</publishedDay><publishedMonth>1</publishedMonth><publishedYear>2021</publishedYear><publishedDate>2021-01-01</publishedDate><doi>10.1007/s00204-020-02902-3</doi><url/><notes/><college>COLLEGE NANME</college><department>Biomedical Sciences</department><CollegeCode>COLLEGE CODE</CollegeCode><DepartmentCode>BMS</DepartmentCode><institution>Swansea University</institution><apcterm/><lastEdited>2021-02-09T16:01:59.1440104</lastEdited><Created>2020-09-16T11:26:10.3379145</Created><path><level id="1">Faculty of Medicine, Health and Life Sciences</level><level id="2">Swansea University Medical School - Medicine</level></path><authors><author><firstname>Katherine</firstname><surname>Chapman</surname><orcid>0000-0001-6668-0705</orcid><order>1</order></author><author><firstname>Eleanor</firstname><surname>Wilde</surname><order>2</order></author><author><firstname>Fiona M.</firstname><surname>Chapman</surname><order>3</order></author><author><firstname>Jatin</firstname><surname>Verma</surname><order>4</order></author><author><firstname>Ume-kulsoom</firstname><surname>Shah</surname><orcid>0000-0002-0594-580X</orcid><order>5</order></author><author><firstname>Leanne</firstname><surname>Stannard</surname><order>6</order></author><author><firstname>Anna</firstname><surname>Seager</surname><orcid>0000-0001-8926-5504</orcid><order>7</order></author><author><firstname>James</firstname><surname>Tonkin</surname><orcid/><order>8</order></author><author><firstname>Rowan</firstname><surname>Brown</surname><orcid>0000-0003-3628-2524</orcid><order>9</order></author><author><firstname>Ann T.</firstname><surname>Doherty</surname><order>10</order></author><author><firstname>George</firstname><surname>Johnson</surname><order>11</order></author><author><firstname>Shareen</firstname><surname>Doak</surname><orcid>0000-0002-6753-1987</orcid><order>12</order></author><author><firstname>Gareth</firstname><surname>Jenkins</surname><orcid>0000-0002-5437-8389</orcid><order>13</order></author></authors><documents><document><filename>55186__18359__b5f156f08e5d4ed9bbdcc8a37f5027bb.pdf</filename><originalFilename>55186.pdf</originalFilename><uploaded>2020-10-07T16:41:29.8222315</uploaded><type>Output</type><contentLength>1082303</contentLength><contentType>application/pdf</contentType><version>Version of Record</version><cronfaStatus>true</cronfaStatus><documentNotes>© 2020 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution 4.0 (CC BY) License</documentNotes><copyrightCorrect>true</copyrightCorrect><language>eng</language><licence>http://creativecommons.org/licenses/by/4.0/</licence></document></documents><OutputDurs/></rfc1807>
spelling	2021-02-09T16:01:59.1440104 v2 55186 2020-09-16 Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action 19e7d85eec17117858d867ec0c9f575e 0000-0001-6668-0705 Katherine Chapman Katherine Chapman true false 664c7183e97777f8215222d0f5c8831d Eleanor Wilde Eleanor Wilde true false 6c11cec3815148d928211f6648a6dce9 Jatin Verma Jatin Verma true false bcef4e069220a4b85f8a2c0cc3059487 0000-0002-0594-580X Ume-kulsoom Shah Ume-kulsoom Shah true false 4a21f43a6d275fb4908405b05e60dc5f Leanne Stannard Leanne Stannard true false bc76a4c997d4384daa4cc1a52a27ed64 0000-0001-8926-5504 Anna Seager Anna Seager true false b6421e6d425db934fbe521640605b010 James Tonkin James Tonkin true false d7db8d42c476dfa69c15ce06d29bd863 0000-0003-3628-2524 Rowan Brown Rowan Brown true false 97544e9483ec5a71957b53dd2c87a6d9 George Johnson George Johnson true false 8f70286908f67238a527a98cbf66d387 0000-0002-6753-1987 Shareen Doak Shareen Doak true false a44095d26187304e903da7ca778697b6 0000-0002-5437-8389 Gareth Jenkins Gareth Jenkins true false 2020-09-16 BMS Journal Article Archives of Toxicology 95 1 321 336 Springer Science and Business Media LLC 0340-5761 1432-0738 In vitro; Carcinogenicity testing; Genotoxicity; Multiple endpoints 1 1 2021 2021-01-01 10.1007/s00204-020-02902-3 COLLEGE NANME Biomedical Sciences COLLEGE CODE BMS Swansea University 2021-02-09T16:01:59.1440104 2020-09-16T11:26:10.3379145 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Katherine Chapman 0000-0001-6668-0705 1 Eleanor Wilde 2 Fiona M. Chapman 3 Jatin Verma 4 Ume-kulsoom Shah 0000-0002-0594-580X 5 Leanne Stannard 6 Anna Seager 0000-0001-8926-5504 7 James Tonkin 8 Rowan Brown 0000-0003-3628-2524 9 Ann T. Doherty 10 George Johnson 11 Shareen Doak 0000-0002-6753-1987 12 Gareth Jenkins 0000-0002-5437-8389 13 55186__18359__b5f156f08e5d4ed9bbdcc8a37f5027bb.pdf 55186.pdf 2020-10-07T16:41:29.8222315 Output 1082303 application/pdf Version of Record true © 2020 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution 4.0 (CC BY) License true eng http://creativecommons.org/licenses/by/4.0/
title	Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action
spellingShingle	Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action Katherine Chapman Eleanor Wilde Jatin Verma Ume-kulsoom Shah Leanne Stannard Anna Seager James Tonkin Rowan Brown George Johnson Shareen Doak Gareth Jenkins
title_short	Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action
title_full	Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action
title_fullStr	Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action
title_full_unstemmed	Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action
title_sort	Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action
author_id_str_mv	19e7d85eec17117858d867ec0c9f575e 664c7183e97777f8215222d0f5c8831d 6c11cec3815148d928211f6648a6dce9 bcef4e069220a4b85f8a2c0cc3059487 4a21f43a6d275fb4908405b05e60dc5f bc76a4c997d4384daa4cc1a52a27ed64 b6421e6d425db934fbe521640605b010 d7db8d42c476dfa69c15ce06d29bd863 97544e9483ec5a71957b53dd2c87a6d9 8f70286908f67238a527a98cbf66d387 a44095d26187304e903da7ca778697b6
author_id_fullname_str_mv	19e7d85eec17117858d867ec0c9f575e_*_Katherine Chapman 664c7183e97777f8215222d0f5c8831d__Eleanor Wilde 6c11cec3815148d928211f6648a6dce9__Jatin Verma bcef4e069220a4b85f8a2c0cc3059487__Ume-kulsoom Shah 4a21f43a6d275fb4908405b05e60dc5f__Leanne Stannard bc76a4c997d4384daa4cc1a52a27ed64__Anna Seager b6421e6d425db934fbe521640605b010__James Tonkin d7db8d42c476dfa69c15ce06d29bd863__Rowan Brown 97544e9483ec5a71957b53dd2c87a6d9__George Johnson 8f70286908f67238a527a98cbf66d387__Shareen Doak a44095d26187304e903da7ca778697b6_**_Gareth Jenkins
author	Katherine Chapman Eleanor Wilde Jatin Verma Ume-kulsoom Shah Leanne Stannard Anna Seager James Tonkin Rowan Brown George Johnson Shareen Doak Gareth Jenkins
author2	Katherine Chapman Eleanor Wilde Fiona M. Chapman Jatin Verma Ume-kulsoom Shah Leanne Stannard Anna Seager James Tonkin Rowan Brown Ann T. Doherty George Johnson Shareen Doak Gareth Jenkins
format	Journal article
container_title	Archives of Toxicology
container_volume	95
container_issue	1
container_start_page	321
publishDate	2021
institution	Swansea University
issn	0340-5761 1432-0738
doi_str_mv	10.1007/s00204-020-02902-3
publisher	Springer Science and Business Media LLC
college_str	Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id	facultyofmedicinehealthandlifesciences
hierarchy_top_title	Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id	facultyofmedicinehealthandlifesciences
hierarchy_parent_title	Faculty of Medicine, Health and Life Sciences
department_str	Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
document_store_str	1
active_str	0
published_date	2021-01-01T04:09:13Z
_version_	1763753646751744000
score	11.016235

Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action

Similar Items