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Concerning P450 Evolution: Structural Analyses Support Bacterial Origin of Sterol 14α-Demethylases

David Lamb Orcid Logo, Tatiana Y Hargrove, Bin Zhao, Zdzislaw Wawrzak, Jared V Goldstone, William David Nes, Steven Kelly Orcid Logo, Michael R Waterman, John J Stegeman, Galina I Lepesheva

Molecular Biology and Evolution, Volume: 38, Issue: 3, Pages: 952 - 967

Swansea University Authors: David Lamb Orcid Logo, Steven Kelly Orcid Logo

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DOI (Published version): 10.1093/molbev/msaa260

Published in: Molecular Biology and Evolution
ISSN: 0737-4038 1537-1719
Published: Oxford University Press (OUP) 2021
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Keywords: sterol biosynthesis, evolution, cytochrome P450, CYP51 redox partner, crystallography
College: Faculty of Medicine, Health and Life Sciences
Issue: 3
Start Page: 952
End Page: 967