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Sepsis target validation for repurposing and combining complement and immune checkpoint inhibition therapeutics

Patrícia R.S. Rodrigues, Noemi Picco Orcid Logo, B Paul Morgan, Peter Ghazal

Expert Opinion on Drug Discovery, Volume: 16, Issue: 5, Pages: 537 - 551

Swansea University Author: Noemi Picco Orcid Logo

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Published in: Expert Opinion on Drug Discovery
ISSN: 1746-0441 1746-045X
Published: Informa UK Limited 2021
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Keywords: Anaphylatoxins; c5a; complement; immune checkpoint; pattern recognition molecules (PRMs); sepsis; t-cell dysfunction; biologic-therapy
College: Faculty of Science and Engineering
Issue: 5
Start Page: 537
End Page: 551