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Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial

Matthias von Herrath, Steve Bain Orcid Logo, Bruce Bode, Jesper Ole Clausen, Ken Coppieters, Leylya Gaysina, Janusz Gumprecht, Troels Krarup Hansen, Chantal Mathieu, Cristobal Morales, Ofri Mosenzon, Stine Segel, George Tsoukas, Thomas R Pieber, Bernhard Ludvik, Rudolf Prager, Bernhard Paulweber, Christoph F Ebenbichler, B Keymeulen, C De Block, Loren Grossman, Robyn Houlden, Patrice Perron, Thomas Ransom, Peter Senior, S. John Weisnagel, Vincent Woo, Richard Dumas, David Thompson, Tina Vilsbøll, Jeppe Gram, Claus Bogh Juhl, Janne Hukkanen, Jorma Lahtela, Leo Niskanen, Donal O'Shea, Timothy O'Brien, Seamus Sreenan, Julio Wainstein, Moshe Phillip, Hilla Knobler, Francesco Dotta, Pier Marco Piatti, Trevisan Roberto, Agostino Gnasso, Hanne Gulseth, John Cooper, Ewa Pankowska, Monika Lukaszewicz, Bogumił Wolnik, Isabel Manita, Olinda Marques, Cristina Roque, Rosa Maria Príncipe, Celestino Neves, Susana Heitor, L Ruyatkina, Irina Dvoryashina, Gulnar Vagapova, Lidiya Belousova, Marina Sergeeva-Kondrachenko, Andrey Peskov, Elena Frolova, Albina Golovach, Marina Kunitsyna, Natalia Krasnopeeva (Kabachkova), Irina Ipatko, Carmen De la Cuesta, Francisco José Tinahones, Mercedes Rigla, Juan Francisco Merino, Luis Alberto Gómez, Mercè Fernández, Rafael Simó, Mikael Rydén, Johan Jendle, Karin Filipsson, Björn Eliasson, Borys Mankovsky, Iurii Lymar, Liubov Sokolova, Galyna Myshanych, Tetiana Zlova, Maryna Vlasenko, Petro Kuskalo -, Hamish Courtney, Colin Dayan, Patrick English, Simon Heller, Andrew B Johnson, Sunil Nair, R. D Leslie, P Narendran, Nick Oliver, Shenaz Ramtoola, Jim Shaw, Adie Viljoen -, Amer Al-Karadsheh, Jean Marie Dostou, Sumana Gangi, Peter Gottlieb, Terri Jerkins, Michael Magnotti, Jennifer Marks, Samer Nakhle, Gholamreza Bonabi, Lyle Myers, Richard Pratley, William Hagopian, Jeremy Pettus, Bernt Johan von Scholten, Johnna D Wesley, Frederik F Kreiner

The Lancet Diabetes & Endocrinology, Volume: 9, Issue: 4, Pages: 212 - 224

Swansea University Author: Steve Bain Orcid Logo

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Published in: The Lancet Diabetes & Endocrinology
ISSN: 2213-8587
Published: Elsevier BV 2021
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spelling 2021-05-28T19:15:13.9620293 v2 56262 2021-02-16 Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial 5399f4c6e6a70f3608a084ddb938511a 0000-0001-8519-4964 Steve Bain Steve Bain true false 2021-02-16 BMS Journal Article The Lancet Diabetes & Endocrinology 9 4 212 224 Elsevier BV 2213-8587 1 4 2021 2021-04-01 10.1016/s2213-8587(21)00019-x COLLEGE NANME Biomedical Sciences COLLEGE CODE BMS Swansea University 2021-05-28T19:15:13.9620293 2021-02-16T11:54:12.9685874 Swansea University Medical School Swansea University Medical School Matthias von Herrath 1 Steve Bain 0000-0001-8519-4964 2 Bruce Bode 3 Jesper Ole Clausen 4 Ken Coppieters 5 Leylya Gaysina 6 Janusz Gumprecht 7 Troels Krarup Hansen 8 Chantal Mathieu 9 Cristobal Morales 10 Ofri Mosenzon 11 Stine Segel 12 George Tsoukas 13 Thomas R Pieber 14 Bernhard Ludvik 15 Rudolf Prager 16 Bernhard Paulweber 17 Christoph F Ebenbichler 18 B Keymeulen 19 C De Block 20 Loren Grossman 21 Robyn Houlden 22 Patrice Perron 23 Thomas Ransom 24 Peter Senior 25 S. John Weisnagel 26 Vincent Woo 27 Richard Dumas 28 David Thompson 29 Tina Vilsbøll 30 Jeppe Gram 31 Claus Bogh Juhl 32 Janne Hukkanen 33 Jorma Lahtela 34 Leo Niskanen 35 Donal O'Shea 36 Timothy O'Brien 37 Seamus Sreenan 38 Julio Wainstein 39 Moshe Phillip 40 Hilla Knobler 41 Francesco Dotta 42 Pier Marco Piatti 43 Trevisan Roberto 44 Agostino Gnasso 45 Hanne Gulseth 46 John Cooper 47 Ewa Pankowska 48 Monika Lukaszewicz 49 Bogumił Wolnik 50 Isabel Manita 51 Olinda Marques 52 Cristina Roque 53 Rosa Maria Príncipe 54 Celestino Neves 55 Susana Heitor 56 L Ruyatkina 57 Irina Dvoryashina 58 Gulnar Vagapova 59 Lidiya Belousova 60 Marina Sergeeva-Kondrachenko 61 Andrey Peskov 62 Elena Frolova 63 Albina Golovach 64 Marina Kunitsyna 65 Natalia Krasnopeeva (Kabachkova) 66 Irina Ipatko 67 Carmen De la Cuesta 68 Francisco José Tinahones 69 Mercedes Rigla 70 Juan Francisco Merino 71 Luis Alberto Gómez 72 Mercè Fernández 73 Rafael Simó 74 Mikael Rydén 75 Johan Jendle 76 Karin Filipsson 77 Björn Eliasson 78 Borys Mankovsky 79 Iurii Lymar 80 Liubov Sokolova 81 Galyna Myshanych 82 Tetiana Zlova 83 Maryna Vlasenko 84 Petro Kuskalo - 85 Hamish Courtney 86 Colin Dayan 87 Patrick English 88 Simon Heller 89 Andrew B Johnson 90 Sunil Nair 91 R. D Leslie 92 P Narendran 93 Nick Oliver 94 Shenaz Ramtoola 95 Jim Shaw 96 Adie Viljoen - 97 Amer Al-Karadsheh 98 Jean Marie Dostou 99 Sumana Gangi 100 Peter Gottlieb 101 Terri Jerkins 102 Michael Magnotti 103 Jennifer Marks 104 Samer Nakhle 105 Gholamreza Bonabi 106 Lyle Myers 107 Richard Pratley 108 William Hagopian 109 Jeremy Pettus 110 Bernt Johan von Scholten 111 Johnna D Wesley 112 Frederik F Kreiner 113 56262__19310__11e5c20784a9456584b8f416cb636012.pdf von Herrath2021.pdf 2021-02-16T12:13:01.5217008 Output 1968921 application/pdf Accepted Manuscript true 2021-09-01T00:00:00.0000000 ©2021 All rights reserved. All article content, except where otherwise noted, is licensed under a Creative Commons Attribution Non-Commercial No Derivatives License (CC-BY-NC-ND) true eng https://creativecommons.org/licenses/by-nc-nd/4.0/
title Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial
spellingShingle Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial
Steve Bain
title_short Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial
title_full Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial
title_fullStr Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial
title_full_unstemmed Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial
title_sort Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial
author_id_str_mv 5399f4c6e6a70f3608a084ddb938511a
author_id_fullname_str_mv 5399f4c6e6a70f3608a084ddb938511a_***_Steve Bain
author Steve Bain
author2 Matthias von Herrath
Steve Bain
Bruce Bode
Jesper Ole Clausen
Ken Coppieters
Leylya Gaysina
Janusz Gumprecht
Troels Krarup Hansen
Chantal Mathieu
Cristobal Morales
Ofri Mosenzon
Stine Segel
George Tsoukas
Thomas R Pieber
Bernhard Ludvik
Rudolf Prager
Bernhard Paulweber
Christoph F Ebenbichler
B Keymeulen
C De Block
Loren Grossman
Robyn Houlden
Patrice Perron
Thomas Ransom
Peter Senior
S. John Weisnagel
Vincent Woo
Richard Dumas
David Thompson
Tina Vilsbøll
Jeppe Gram
Claus Bogh Juhl
Janne Hukkanen
Jorma Lahtela
Leo Niskanen
Donal O'Shea
Timothy O'Brien
Seamus Sreenan
Julio Wainstein
Moshe Phillip
Hilla Knobler
Francesco Dotta
Pier Marco Piatti
Trevisan Roberto
Agostino Gnasso
Hanne Gulseth
John Cooper
Ewa Pankowska
Monika Lukaszewicz
Bogumił Wolnik
Isabel Manita
Olinda Marques
Cristina Roque
Rosa Maria Príncipe
Celestino Neves
Susana Heitor
L Ruyatkina
Irina Dvoryashina
Gulnar Vagapova
Lidiya Belousova
Marina Sergeeva-Kondrachenko
Andrey Peskov
Elena Frolova
Albina Golovach
Marina Kunitsyna
Natalia Krasnopeeva (Kabachkova)
Irina Ipatko
Carmen De la Cuesta
Francisco José Tinahones
Mercedes Rigla
Juan Francisco Merino
Luis Alberto Gómez
Mercè Fernández
Rafael Simó
Mikael Rydén
Johan Jendle
Karin Filipsson
Björn Eliasson
Borys Mankovsky
Iurii Lymar
Liubov Sokolova
Galyna Myshanych
Tetiana Zlova
Maryna Vlasenko
Petro Kuskalo -
Hamish Courtney
Colin Dayan
Patrick English
Simon Heller
Andrew B Johnson
Sunil Nair
R. D Leslie
P Narendran
Nick Oliver
Shenaz Ramtoola
Jim Shaw
Adie Viljoen -
Amer Al-Karadsheh
Jean Marie Dostou
Sumana Gangi
Peter Gottlieb
Terri Jerkins
Michael Magnotti
Jennifer Marks
Samer Nakhle
Gholamreza Bonabi
Lyle Myers
Richard Pratley
William Hagopian
Jeremy Pettus
Bernt Johan von Scholten
Johnna D Wesley
Frederik F Kreiner
format Journal article
container_title The Lancet Diabetes & Endocrinology
container_volume 9
container_issue 4
container_start_page 212
publishDate 2021
institution Swansea University
issn 2213-8587
doi_str_mv 10.1016/s2213-8587(21)00019-x
publisher Elsevier BV
college_str Swansea University Medical School
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hierarchy_top_title Swansea University Medical School
hierarchy_parent_id swanseauniversitymedicalschool
hierarchy_parent_title Swansea University Medical School
department_str Swansea University Medical School{{{_:::_}}}Swansea University Medical School{{{_:::_}}}Swansea University Medical School
document_store_str 1
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published_date 2021-04-01T04:29:16Z
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