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The e-psychonaut drugs’ psychopharmacology / Fabrizio Schifano, Stefania Chiappini, John M. Corkery, Norbert Scherbaum, Amira Guirguis

Current Opinion in Pharmacology, Volume: 57, Pages: 165 - 174

Swansea University Author: Amira Guirguis

  • Accepted Manuscript under embargo until: 25th March 2022

Abstract

The focus here was on the pharmacological and clinical pharmacological issues pertaining to the vast range of drugs (e.g., synthetic cannabimimetics; synthetic opioids; novel stimulants; novel psychedelics; PCP/ketamine-like compounds; prescribed medicinal compounds; and popular psychotropic herbs/p...

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Published in: Current Opinion in Pharmacology
ISSN: 1471-4892
Published: UK Elsevier BV 2021
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa56315
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Abstract: The focus here was on the pharmacological and clinical pharmacological issues pertaining to the vast range of drugs (e.g., synthetic cannabimimetics; synthetic opioids; novel stimulants; novel psychedelics; PCP/ketamine-like compounds; prescribed medicinal compounds; and popular psychotropic herbs/plants) discussed by Internet-based, new/novel psychoactive substances (NPS) enthusiasts, ‘e-psychonauts’.Currently ongoing related in silico studies, followed by further in vitro and in vivo/preclinical studies, will hopefully provide important findings in terms of which molecules within each given NPS class may present with higher levels of receptor affinities, and hence clinical potency. Understanding the pharmacological characteristics/potency of those novel recreational molecules will hopefully help in predicting related NPS diffusion, morbidity, and possible lethality data.
Keywords: e-psychonauts; psychopharmacology; addiction; new psychoactive substances; novel psychoactive substances; NPS; drug abuse
College: Swansea University Medical School
Start Page: 165
End Page: 174