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Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity

Jenny Desantis, Giulio Nannetti Orcid Logo, Serena Massari, Maria Letizia Barreca, Giuseppe Manfroni, Violetta Cecchetti, Giorgio Palù, Laura Goracci, Arianna Loregian, Oriana Tabarrini

European Journal of Medicinal Chemistry, Volume: 138, Pages: 128 - 139

Swansea University Author: Giulio Nannetti Orcid Logo

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Published in: European Journal of Medicinal Chemistry
ISSN: 0223-5234
Published: Elsevier BV 2017
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Keywords: PA-PB1 interaction; Influenza virus polymerase; Protein-protein interaction inhibitors; Influenza virus inhibitors
College: Swansea University Medical School
Start Page: 128
End Page: 139