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A Narrative Review of Chronic Kidney Disease in Clinical Practice: Current Challenges and Future Perspectives
Advances in Therapy, Volume: 39, Issue: 1, Pages: 33 - 43
Swansea University Author: Steve Bain
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DOI (Published version): 10.1007/s12325-021-01927-z
Abstract
Chronic kidney disease (CKD) is a complex disease which affects approximately 13% of the world's population. Over time, CKD can cause renal dysfunction and progression to end-stage kidney disease and cardiovascular disease. Complications associated with CKD may contribute to the acceleration of...
Published in: | Advances in Therapy |
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ISSN: | 0741-238X 1865-8652 |
Published: |
Springer Science and Business Media LLC
2022
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URI: | https://cronfa.swan.ac.uk/Record/cronfa58735 |
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2022-03-17T04:27:21Z |
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2022-03-16T11:38:58.3506881 v2 58735 2021-11-22 A Narrative Review of Chronic Kidney Disease in Clinical Practice: Current Challenges and Future Perspectives 5399f4c6e6a70f3608a084ddb938511a 0000-0001-8519-4964 Steve Bain Steve Bain true false 2021-11-22 MEDS Chronic kidney disease (CKD) is a complex disease which affects approximately 13% of the world's population. Over time, CKD can cause renal dysfunction and progression to end-stage kidney disease and cardiovascular disease. Complications associated with CKD may contribute to the acceleration of disease progression and the risk of cardiovascular-related morbidities. Early CKD is asymptomatic, and symptoms only present at later stages when complications of the disease arise, such as a decline in kidney function and the presence of other comorbidities associated with the disease. In advanced stages of the disease, when kidney function is significantly impaired, patients can only be treated with dialysis or a transplant. With limited treatment options available, an increasing prevalence of both the elderly population and comorbidities associated with the disease, the prevalence of CKD is set to rise. This review discusses the current challenges and the unmet patient need in CKD. Journal Article Advances in Therapy 39 1 33 43 Springer Science and Business Media LLC 0741-238X 1865-8652 Cardiovascular disease, Chronic kidney disease, Diabetic kidney disease, Sodium–glucose co-transporter 2 inhibitors 1 1 2022 2022-01-01 10.1007/s12325-021-01927-z COLLEGE NANME Medical School COLLEGE CODE MEDS Swansea University Other AstraZeneca UK Ltd 2022-03-16T11:38:58.3506881 2021-11-22T11:26:29.9041027 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Marc Evans 1 Ruth D. Lewis 2 Angharad R. Morgan 3 Martin B. Whyte 4 Wasim Hanif 5 Steve Bain 0000-0001-8519-4964 6 Sarah Davies 7 Umesh Dashora 8 Zaheer Yousef 9 Dipesh C. Patel 10 W. David Strain 11 58735__21622__f384d308918d4b9f8e7868e8fa280f9f.pdf 58735.pdf 2021-11-22T11:27:58.1719750 Output 361930 application/pdf Version of Record true Copyright: The Author(s) 2021. This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License true eng http://creativecommons.org/licenses/by-nc/4.0/ |
title |
A Narrative Review of Chronic Kidney Disease in Clinical Practice: Current Challenges and Future Perspectives |
spellingShingle |
A Narrative Review of Chronic Kidney Disease in Clinical Practice: Current Challenges and Future Perspectives Steve Bain |
title_short |
A Narrative Review of Chronic Kidney Disease in Clinical Practice: Current Challenges and Future Perspectives |
title_full |
A Narrative Review of Chronic Kidney Disease in Clinical Practice: Current Challenges and Future Perspectives |
title_fullStr |
A Narrative Review of Chronic Kidney Disease in Clinical Practice: Current Challenges and Future Perspectives |
title_full_unstemmed |
A Narrative Review of Chronic Kidney Disease in Clinical Practice: Current Challenges and Future Perspectives |
title_sort |
A Narrative Review of Chronic Kidney Disease in Clinical Practice: Current Challenges and Future Perspectives |
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5399f4c6e6a70f3608a084ddb938511a |
author_id_fullname_str_mv |
5399f4c6e6a70f3608a084ddb938511a_***_Steve Bain |
author |
Steve Bain |
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Marc Evans Ruth D. Lewis Angharad R. Morgan Martin B. Whyte Wasim Hanif Steve Bain Sarah Davies Umesh Dashora Zaheer Yousef Dipesh C. Patel W. David Strain |
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Advances in Therapy |
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Swansea University |
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0741-238X 1865-8652 |
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10.1007/s12325-021-01927-z |
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Springer Science and Business Media LLC |
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Faculty of Medicine, Health and Life Sciences |
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Chronic kidney disease (CKD) is a complex disease which affects approximately 13% of the world's population. Over time, CKD can cause renal dysfunction and progression to end-stage kidney disease and cardiovascular disease. Complications associated with CKD may contribute to the acceleration of disease progression and the risk of cardiovascular-related morbidities. Early CKD is asymptomatic, and symptoms only present at later stages when complications of the disease arise, such as a decline in kidney function and the presence of other comorbidities associated with the disease. In advanced stages of the disease, when kidney function is significantly impaired, patients can only be treated with dialysis or a transplant. With limited treatment options available, an increasing prevalence of both the elderly population and comorbidities associated with the disease, the prevalence of CKD is set to rise. This review discusses the current challenges and the unmet patient need in CKD. |
published_date |
2022-01-01T14:10:18Z |
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11.414753 |