Journal article 693 views 76 downloads
Inspiratory Muscle Training Enhances Recovery Post COVID-19: A Randomised Controlled Trial
,
Ronan M G Berg,
James Shelley,
Joanne Hudson ,
Zoe L Saynor,
Jamie Duckers ,
Keir Lewis,
Gwyneth Davies ,
Kelly Mackintosh
European Respiratory Journal, Volume: 60, Issue: 6, Start page: 2103101
Swansea University Authors:
Melitta McNarry , James Shelley, Joanne Hudson , Gwyneth Davies , Kelly Mackintosh
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Copyright ©The authors 2022. This version is distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. For commercial reproduction rights and permissions contactpermissions@ersnet.org
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DOI (Published version): 10.1183/13993003.03101-2021
Abstract
Background: Many people recovering from COVID-19 experience prolonged symptoms, particularly breathlessness. We urgently need to identify safe and effective COVID-19 rehabilitative strategies. The aim of the current study was to investigate the potential rehabilitative role of inspiratory muscle tra...
| Published in: | European Respiratory Journal |
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| ISSN: | 0903-1936 1399-3003 |
| Published: |
European Respiratory Society (ERS)
2022
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| Online Access: |
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa59407 |
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| Abstract: |
Background: Many people recovering from COVID-19 experience prolonged symptoms, particularly breathlessness. We urgently need to identify safe and effective COVID-19 rehabilitative strategies. The aim of the current study was to investigate the potential rehabilitative role of inspiratory muscle training (IMT).Methods: 281 adults (46.6±12.2 years; 88% female) recovering from self-reported COVID-19 (9.0±4.2 months post-acute infection) were randomized 4:1 to an eight-week IMT or a “usual care” wait list control arm. Health-related quality of life and breathlessness questionnaires (King’s Brief Interstitial Lung Disease (KBILD) and Transition Dyspnoea Index (TDI)), respiratory muscle strength and fitness (Chester Step Test) were assessed pre- and post-intervention. The primary endpoint was KBILD total score, with the KBILD subdomains and TDI being key secondary outcomes. Results: According to intention to treat (ITT), there was no difference between groups in KBILD total score post-intervention (Control: 59.5±12.4; IMT: 58.2±12.3; P<0.05) but IMT elicited clinically meaningful improvements in the KBILD subdomains of breathlessness (Control: 59.8±12.6; IMT: 62.2±16.2; P<0.05) and chest symptoms (Control: 59.2±18.7; IMT: 64.5±18.2; P<0.05), along with clinically meaningful improvements in breathlessness according to TDI (Control: 0.9 ± 1.7 vs. 2.0 ± 2.0; P<0.05). IMT also improved respiratory muscle strength and estimated aerobic fitness. Conclusions: IMT may represent an important home-based rehabilitation strategy for wider implementation as part of COVID-19 rehabilitative strategies. Given the diverse nature of long-COVID, further research is warranted on the individual responses to rehabilitation - the withdrawal rate herein highlights that no one strategy is likely to be appropriate for all. |
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| Keywords: |
Long COVID; breathlessness; dyspnoea; fitness; physical activity; post-COVID; quality of life |
| College: |
Faculty of Science and Engineering |
| Issue: |
6 |
| Start Page: |
2103101 |