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The Road to Achieving the European Commission's Chemicals Strategy for Nanomaterial Sustainability—A PATROLS Perspective on New Approach Methodologies

Shareen Doak Orcid Logo, Martin Clift Orcid Logo, Anna Costa, Christiaan Delmaar, Ilse Gosens, Sabina Halappanavar, Sean Kelly, Willie J. G. M. Pejinenburg, Barbara Rothen‐Rutishauser, Roel P. F. Schins, Vicki Stone, Lang Tran, Martina G. Vijver, Ulla Vogel, Wendel Wohlleben, Flemming R. Cassee Orcid Logo

Small, Volume: 18, Issue: 17, Start page: 2200231

Swansea University Authors: Shareen Doak Orcid Logo, Martin Clift Orcid Logo

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DOI (Published version): 10.1002/smll.202200231

Abstract

The European Green Deal outlines ambitions to build a more sustainable, climate neutral, and circular economy by 2050. To achieve this, the European Commission has published the Chemicals Strategy for Sustainability: Towards a Toxic-Free Environment, which provides targets for innovation to better p...

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ISSN: 1613-6810 1613-6829
Published: Wiley 2022
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URI: https://cronfa.swan.ac.uk/Record/cronfa59702
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spelling 2022-05-17T14:59:24.2511661 v2 59702 2022-03-25 The Road to Achieving the European Commission's Chemicals Strategy for Nanomaterial Sustainability—A PATROLS Perspective on New Approach Methodologies 8f70286908f67238a527a98cbf66d387 0000-0002-6753-1987 Shareen Doak Shareen Doak true false 71bf49b157691e541950f5c3f49c9169 0000-0001-6133-3368 Martin Clift Martin Clift true false 2022-03-25 BMS The European Green Deal outlines ambitions to build a more sustainable, climate neutral, and circular economy by 2050. To achieve this, the European Commission has published the Chemicals Strategy for Sustainability: Towards a Toxic-Free Environment, which provides targets for innovation to better protect human and environmental health, including challenges posed by hazardous chemicals and animal testing. The European project PATROLS (Physiologically Anchored Tools for Realistic nanOmateriaL hazard aSsessment) has addressed multiple aspects of the Chemicals Strategy for Sustainability by establishing a battery of new approach methodologies, including physiologically anchored human and environmental hazard assessment tools to evaluate the safety of engineered nanomaterials. PATROLS has delivered and improved innovative tools to support regulatory decision-making processes. These tools also support the need for reducing regulated vertebrate animal testing; when used at an early stage of the innovation pipeline, the PATROLS tools facilitate the safe and sustainable development of new nano-enabled products before they reach the market. Journal Article Small 18 17 2200231 Wiley 1613-6810 1613-6829 ecotoxicity; in silico models; in vitro 3D models; nanomaterials; nanosafety; physico-chemical characterization 27 4 2022 2022-04-27 10.1002/smll.202200231 COLLEGE NANME Biomedical Sciences COLLEGE CODE BMS Swansea University SU Library paid the OA fee (TA Institutional Deal) European Union's Horizon 2020. Grant Number: 760813; Horizon 2020 Framework Programme. Grant Number: 760813 2022-05-17T14:59:24.2511661 2022-03-25T06:41:05.8015553 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine Shareen Doak 0000-0002-6753-1987 1 Martin Clift 0000-0001-6133-3368 2 Anna Costa 3 Christiaan Delmaar 4 Ilse Gosens 5 Sabina Halappanavar 6 Sean Kelly 7 Willie J. G. M. Pejinenburg 8 Barbara Rothen‐Rutishauser 9 Roel P. F. Schins 10 Vicki Stone 11 Lang Tran 12 Martina G. Vijver 13 Ulla Vogel 14 Wendel Wohlleben 15 Flemming R. Cassee 0000-0001-9958-8630 16 59702__23910__26ead4d711324fe98f4139b15dfd5272.pdf 59702.pdf 2022-04-25T15:44:56.4325962 Output 1499158 application/pdf Version of Record true © 2022 The Authors. Small published by Wiley-VCH GmbH. This is an open access article under the terms of the Creative Commons Attribution License true eng http://creativecommons.org/licenses/by/4.0/
title The Road to Achieving the European Commission's Chemicals Strategy for Nanomaterial Sustainability—A PATROLS Perspective on New Approach Methodologies
spellingShingle The Road to Achieving the European Commission's Chemicals Strategy for Nanomaterial Sustainability—A PATROLS Perspective on New Approach Methodologies
Shareen Doak
Martin Clift
title_short The Road to Achieving the European Commission's Chemicals Strategy for Nanomaterial Sustainability—A PATROLS Perspective on New Approach Methodologies
title_full The Road to Achieving the European Commission's Chemicals Strategy for Nanomaterial Sustainability—A PATROLS Perspective on New Approach Methodologies
title_fullStr The Road to Achieving the European Commission's Chemicals Strategy for Nanomaterial Sustainability—A PATROLS Perspective on New Approach Methodologies
title_full_unstemmed The Road to Achieving the European Commission's Chemicals Strategy for Nanomaterial Sustainability—A PATROLS Perspective on New Approach Methodologies
title_sort The Road to Achieving the European Commission's Chemicals Strategy for Nanomaterial Sustainability—A PATROLS Perspective on New Approach Methodologies
author_id_str_mv 8f70286908f67238a527a98cbf66d387
71bf49b157691e541950f5c3f49c9169
author_id_fullname_str_mv 8f70286908f67238a527a98cbf66d387_***_Shareen Doak
71bf49b157691e541950f5c3f49c9169_***_Martin Clift
author Shareen Doak
Martin Clift
author2 Shareen Doak
Martin Clift
Anna Costa
Christiaan Delmaar
Ilse Gosens
Sabina Halappanavar
Sean Kelly
Willie J. G. M. Pejinenburg
Barbara Rothen‐Rutishauser
Roel P. F. Schins
Vicki Stone
Lang Tran
Martina G. Vijver
Ulla Vogel
Wendel Wohlleben
Flemming R. Cassee
format Journal article
container_title Small
container_volume 18
container_issue 17
container_start_page 2200231
publishDate 2022
institution Swansea University
issn 1613-6810
1613-6829
doi_str_mv 10.1002/smll.202200231
publisher Wiley
college_str Faculty of Medicine, Health and Life Sciences
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hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
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description The European Green Deal outlines ambitions to build a more sustainable, climate neutral, and circular economy by 2050. To achieve this, the European Commission has published the Chemicals Strategy for Sustainability: Towards a Toxic-Free Environment, which provides targets for innovation to better protect human and environmental health, including challenges posed by hazardous chemicals and animal testing. The European project PATROLS (Physiologically Anchored Tools for Realistic nanOmateriaL hazard aSsessment) has addressed multiple aspects of the Chemicals Strategy for Sustainability by establishing a battery of new approach methodologies, including physiologically anchored human and environmental hazard assessment tools to evaluate the safety of engineered nanomaterials. PATROLS has delivered and improved innovative tools to support regulatory decision-making processes. These tools also support the need for reducing regulated vertebrate animal testing; when used at an early stage of the innovation pipeline, the PATROLS tools facilitate the safe and sustainable development of new nano-enabled products before they reach the market.
published_date 2022-04-27T04:17:12Z
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