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Brief lifestyle interventions for prediabetes in primary care: a service evaluation

Rhys Thatcher, Nicholas Gregory, Ivy Cheung, Gareth Dunseath Orcid Logo, Sharon Parsons Orcid Logo, Mark Goodwin, Steve Luzio Orcid Logo

BMC Primary Care, Volume: 23, Issue: 1

Swansea University Authors: Ivy Cheung, Gareth Dunseath Orcid Logo, Sharon Parsons Orcid Logo, Steve Luzio Orcid Logo

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Abstract

BackgroundThe increasing number of cases of prediabetes in the UK is concerning, particularly in Wales where there is no standard programme of support. The aim of the current service evaluation was to examine the effectiveness of brief lifestyle interventions on glucose tolerance in people at risk o...

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Published in: BMC Primary Care
ISSN: 2731-4553
Published: Springer Science and Business Media LLC 2022
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa60094
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Abstract: BackgroundThe increasing number of cases of prediabetes in the UK is concerning, particularly in Wales where there is no standard programme of support. The aim of the current service evaluation was to examine the effectiveness of brief lifestyle interventions on glucose tolerance in people at risk of developing type 2 diabetes.MethodsIn this pragmatic service evaluation clinical data on people deemed at risk of developing type 2 diabetes were evaluated from two GP clusters. Patients (n = 1207) received a single 15 to 30-min, face-to-face, consultation with a health care practitioner. Interventions were assessed by changes in HbA1c and distribution across the HbA1c ranges 12 months following intervention. Statistical significance of reversion to normoglycaemia and development of diabetes were assessed through comparison with expected rates without intervention.ResultsBetween baseline and 12-month follow-up HbA1c fell from 43.85 ± 1.57 mmol/mol (6.16 ± 0.14%) to 41.63 ± 3.84 mmol/mol (5.96 ± 0.35%), a decrease of 2.22 mmol/mol (0.20%) (95% CI 2.01 (0.18%), 2.42 (0.22%); p < 0.0001). The proportion of people with normal glucose tolerance at 12 months (0.50 95%CI 0.47, 0.52) was significantly larger than the lower (0.06 (p < 0.0001) and the upper (0.19 (p < 0.0001)) estimates based on no intervention.ConclusionResults indicate significant improvement in glucose tolerance across GP clusters. The brief intervention has the potential to offer a robust and effective option to support people at risk of developing type 2 diabetes. Further research in the form of a randomised trial is needed to confirm this and identify those likely to benefit most from this intervention.
Keywords: General Practice; Lifestyle; Prediabetic State; Prevention of Diabetes
College: Swansea University Medical School
Funders: No funding was acquired for the completion of this study.
Issue: 1