No Cover Image

Journal article 88 views

Poly(3,4‐ethylenedioxythiophene):Poly(styrene sulfonate) in antibacterial, tissue engineering and biosensors applications: Progress, challenges and perspectives

Sonal Gupta, Ram Datt, Anamika Mishra, Wing Chung Tsoi Orcid Logo, Asit Patra Orcid Logo, Patrycja Bober

Journal of Applied Polymer Science, Volume: 139, Issue: 30

Swansea University Authors: Ram Datt, Wing Chung Tsoi Orcid Logo

  • Accepted Manuscript under embargo until: 26th May 2023

Check full text

DOI (Published version): 10.1002/app.52663

Abstract

With the advancement of applications in biomedicines and bioelectronics, conducting polymers have attained huge significant attention. For such applications, poly(3,4 ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) is considered a potential conducting polymer because of its low cost, con...

Full description

Published in: Journal of Applied Polymer Science
ISSN: 0021-8995 1097-4628
Published: Wiley 2022
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa60167
Tags: Add Tag
No Tags, Be the first to tag this record!
Abstract: With the advancement of applications in biomedicines and bioelectronics, conducting polymers have attained huge significant attention. For such applications, poly(3,4 ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) is considered a potential conducting polymer because of its low cost, considerable stability, high conductivity and mechanical strength. Most importantly, its easy aqueous solution processability makes it more attractive. Over the last few years, PEDOT:PSS has been predominantly explored and investigated for different optoelectronic flexible devices, and recently it has been studied for biomedical applications. PEDOT:PSS based materials have made progress in biomedicines due to their properties such as biocompatibility, cell proliferation, antibacterial, nontoxicity and so forth. To adjust the desirable properties, special attention is required for altering the structure of PEDOT:PSS material. PEDOT:PSS offers excellent antibacterial properties against both gram-positive and gram-negative bacteria. Moreover, PEDOT:PSS demonstrates an important role in sensing human body humidity, pressure control, glucose detection, as well as employed in human sweat sensors. Besides these, PEDOT:PSS has been studied as a scaffold for endothelial cell preservation. There are several issues which need to be resolved in the future, such as improved biocompatibility and stability to explore the PEDOT:PSS based composite materials in biomedical applications. However, a related review article is lacking, directed on the PEDOT:PSS biomedical applications, namely, antibacterial, tissue engineering, and biosensing. Therefore, the current article summarizes importance of PEDOT:PSS for biomedical applications, and main emphasis is given to its recent advances, challenges and perspectives.
Keywords: biocompatibility; biomaterials; biomedical applications; conducting polymers
College: College of Engineering
Funders: Czech Science Foundation. Grant Number: 21-01401S; SPECIFIC Innovation and Knowledge Centre. Grant Number: EP/N020863/1
Issue: 30