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Secreted Secondary Metabolites Reduce Bacterial Wilt Severity of Tomato in Bacterial–Fungal Co-Infections
,
Grant Nickles ,
Philipp Wiemann,
Nancy P. Keller
Microorganisms, Volume: 9, Issue: 10, Start page: 2123
Swansea University Author:
Claudio Greco
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DOI (Published version): 10.3390/microorganisms9102123
Abstract
In order to gain a comprehensive understanding of plant disease in natural and agricultural ecosystems, it is essential to examine plant disease in multi-pathogen–host systems. Ralstonia solanacearum and Fusarium oxysporum f. sp. lycopersici are vascular wilt pathogens that can result in heavy yield...
| Published in: | Microorganisms |
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| ISSN: | 2076-2607 |
| Published: |
MDPI AG
2021
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| Online Access: |
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| URI: | https://cronfa.swan.ac.uk/Record/cronfa61512 |
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| Abstract: |
In order to gain a comprehensive understanding of plant disease in natural and agricultural ecosystems, it is essential to examine plant disease in multi-pathogen–host systems. Ralstonia solanacearum and Fusarium oxysporum f. sp. lycopersici are vascular wilt pathogens that can result in heavy yield losses in susceptible hosts such as tomato. Although both pathogens occupy the xylem, the costs of mixed infections on wilt disease are unknown. Here, we characterize the consequences of co-infection with R. solanacearum and F. oxysporum using tomato as the model host. Our results demonstrate that bacterial wilt severity is reduced in co-infections, that bikaverin synthesis by Fusarium contributes to bacterial wilt reduction, and that the arrival time of each microbe at the infection court is important in driving the severity of wilt disease. Further, analysis of the co-infection root secretome identified previously uncharacterized secreted metabolites that reduce R. solanacearum growth in vitro and provide protection to tomato seedlings against bacterial wilt disease. Taken together, these results highlight the need to understand the consequences of mixed infections in plant disease. |
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| Keywords: |
secondary metabolites; plant–microbe interactions; coinfection; wilt disease; bacterial–fungal interactions; Fusarium oxysporum; Ralstonia solanacearum |
| College: |
Faculty of Science and Engineering |
| Funders: |
This work was supported by the National Institute of Food and Agriculture, United States
Department of Agriculture, Hatch project 1012878 to N.P.K, the National Institutes of Health under
grant 5R01GM112739-06 to N.P.K. and the UW-Madison Food Research Institute’s E. Michael and
Winona Foster Wisconsin Distinguished Fellowship Award to N.V. |
| Issue: |
10 |
| Start Page: |
2123 |