A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta

M., Betsy D.; Sebastiano, Fabio; Cafolla, Daniele

doi:10.3390/machines8040081

Journal article 156 views 27 downloads

A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta

Betsy D. M. Chaparro-Rico

, Fabio Sebastiano, Daniele Cafolla

Machines, Volume: 8, Issue: 4, Start page: 81

Swansea University Author: Daniele Cafolla

PDF | Version of Record

© 2020 by the authors. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license
Download (3.95MB)

Check full text

DOI (Published version): 10.3390/machines8040081

Abstract

Even though scientific studies of smart stents are extensive, current smart stents focus on pressure sensors. This paper presents a novel implantable biocompatible smart stent for monitoring eventual restenosis. The device is comprised of a metal mesh structure, a biocompatible and adaptable envelop...

Full description

Published in:	Machines
ISSN:	2075-1702
Published:	MDPI AG 2020
Online Access:	Check full text
URI:	https://cronfa.swan.ac.uk/Record/cronfa62498
Tags:	Add Tag No Tags, Be the first to tag this record!

first_indexed	2023-03-01T15:08:29Z
last_indexed	2023-03-02T04:17:37Z
id	cronfa62498
recordtype	SURis
fullrecord	<?xml version="1.0"?><rfc1807><datestamp>2023-03-01T15:10:27.0345073</datestamp><bib-version>v2</bib-version><id>62498</id><entry>2023-02-03</entry><title>A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta</title><swanseaauthors><author><sid>ac4feae4da44720e216ab2e0359e4ddb</sid><ORCID>0000-0002-5602-1519</ORCID><firstname>Daniele</firstname><surname>Cafolla</surname><name>Daniele Cafolla</name><active>true</active><ethesisStudent>false</ethesisStudent></author></swanseaauthors><date>2023-02-03</date><deptcode>SCS</deptcode><abstract>Even though scientific studies of smart stents are extensive, current smart stents focus on pressure sensors. This paper presents a novel implantable biocompatible smart stent for monitoring eventual restenosis. The device is comprised of a metal mesh structure, a biocompatible and adaptable envelope, and pair-operated ultrasonic sensors for restenosis monitoring through flow velocity. Aside from continuous monitoring of restenosis post-implantation, it is also important to evaluate whether the stent design itself causes complications such as restenosis or thrombosis. Therefore, computational fluid dynamic (CFD) analysis before and after stent implantation were carried out as well as finite element analysis (FEA). The proposed smart stent was put in the descending thoracic section of a virtually reconstructed aorta that comes from a computed tomography (CT) scan. Blood flow velocity showed that after stent implantation, there is not liquid retention or vortex generation. In addition, blood pressures after stent implantation were within the normal blood pressure values. The stress and the factor of safety (FOS) analysis showed that the stress values reached by the stent are very far from the yield strength limit of the materials and that the stent is stiff enough to support the applied loads exported from the CFD results.</abstract><type>Journal Article</type><journal>Machines</journal><volume>8</volume><journalNumber>4</journalNumber><paginationStart>81</paginationStart><paginationEnd/><publisher>MDPI AG</publisher><placeOfPublication/><isbnPrint/><isbnElectronic/><issnPrint/><issnElectronic>2075-1702</issnElectronic><keywords>implantable devices; biocompatible; smart stent; restenosis; stent simulation</keywords><publishedDay>24</publishedDay><publishedMonth>11</publishedMonth><publishedYear>2020</publishedYear><publishedDate>2020-11-24</publishedDate><doi>10.3390/machines8040081</doi><url/><notes/><college>COLLEGE NANME</college><department>Computer Science</department><CollegeCode>COLLEGE CODE</CollegeCode><DepartmentCode>SCS</DepartmentCode><institution>Swansea University</institution><apcterm/><funders/><projectreference/><lastEdited>2023-03-01T15:10:27.0345073</lastEdited><Created>2023-02-03T14:17:28.7660727</Created><path><level id="1">Faculty of Science and Engineering</level><level id="2">School of Mathematics and Computer Science - Computer Science</level></path><authors><author><firstname>Betsy D. M.</firstname><surname>Chaparro-Rico</surname><orcid>0000-0002-6874-2508</orcid><order>1</order></author><author><firstname>Fabio</firstname><surname>Sebastiano</surname><order>2</order></author><author><firstname>Daniele</firstname><surname>Cafolla</surname><orcid>0000-0002-5602-1519</orcid><order>3</order></author></authors><documents><document><filename>62498__26715__821a102642c64ed78692873345aa6c26.pdf</filename><originalFilename>62498_VoR.pdf</originalFilename><uploaded>2023-03-01T15:09:06.2334030</uploaded><type>Output</type><contentLength>4141160</contentLength><contentType>application/pdf</contentType><version>Version of Record</version><cronfaStatus>true</cronfaStatus><documentNotes>© 2020 by the authors. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license</documentNotes><copyrightCorrect>true</copyrightCorrect><language>eng</language><licence>http://creativecommons.org/licenses/by/4.0/</licence></document></documents><OutputDurs/></rfc1807>
spelling	2023-03-01T15:10:27.0345073 v2 62498 2023-02-03 A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta ac4feae4da44720e216ab2e0359e4ddb 0000-0002-5602-1519 Daniele Cafolla Daniele Cafolla true false 2023-02-03 SCS Even though scientific studies of smart stents are extensive, current smart stents focus on pressure sensors. This paper presents a novel implantable biocompatible smart stent for monitoring eventual restenosis. The device is comprised of a metal mesh structure, a biocompatible and adaptable envelope, and pair-operated ultrasonic sensors for restenosis monitoring through flow velocity. Aside from continuous monitoring of restenosis post-implantation, it is also important to evaluate whether the stent design itself causes complications such as restenosis or thrombosis. Therefore, computational fluid dynamic (CFD) analysis before and after stent implantation were carried out as well as finite element analysis (FEA). The proposed smart stent was put in the descending thoracic section of a virtually reconstructed aorta that comes from a computed tomography (CT) scan. Blood flow velocity showed that after stent implantation, there is not liquid retention or vortex generation. In addition, blood pressures after stent implantation were within the normal blood pressure values. The stress and the factor of safety (FOS) analysis showed that the stress values reached by the stent are very far from the yield strength limit of the materials and that the stent is stiff enough to support the applied loads exported from the CFD results. Journal Article Machines 8 4 81 MDPI AG 2075-1702 implantable devices; biocompatible; smart stent; restenosis; stent simulation 24 11 2020 2020-11-24 10.3390/machines8040081 COLLEGE NANME Computer Science COLLEGE CODE SCS Swansea University 2023-03-01T15:10:27.0345073 2023-02-03T14:17:28.7660727 Faculty of Science and Engineering School of Mathematics and Computer Science - Computer Science Betsy D. M. Chaparro-Rico 0000-0002-6874-2508 1 Fabio Sebastiano 2 Daniele Cafolla 0000-0002-5602-1519 3 62498__26715__821a102642c64ed78692873345aa6c26.pdf 62498_VoR.pdf 2023-03-01T15:09:06.2334030 Output 4141160 application/pdf Version of Record true © 2020 by the authors. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license true eng http://creativecommons.org/licenses/by/4.0/
title	A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta
spellingShingle	A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta Daniele Cafolla
title_short	A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta
title_full	A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta
title_fullStr	A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta
title_full_unstemmed	A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta
title_sort	A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta
author_id_str_mv	ac4feae4da44720e216ab2e0359e4ddb
author_id_fullname_str_mv	ac4feae4da44720e216ab2e0359e4ddb_***_Daniele Cafolla
author	Daniele Cafolla
author2	Betsy D. M. Chaparro-Rico Fabio Sebastiano Daniele Cafolla
format	Journal article
container_title	Machines
container_volume	8
container_issue	4
container_start_page	81
publishDate	2020
institution	Swansea University
issn	2075-1702
doi_str_mv	10.3390/machines8040081
publisher	MDPI AG
college_str	Faculty of Science and Engineering
hierarchytype
hierarchy_top_id	facultyofscienceandengineering
hierarchy_top_title	Faculty of Science and Engineering
hierarchy_parent_id	facultyofscienceandengineering
hierarchy_parent_title	Faculty of Science and Engineering
department_str	School of Mathematics and Computer Science - Computer Science{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Mathematics and Computer Science - Computer Science
document_store_str	1
active_str	0
description	Even though scientific studies of smart stents are extensive, current smart stents focus on pressure sensors. This paper presents a novel implantable biocompatible smart stent for monitoring eventual restenosis. The device is comprised of a metal mesh structure, a biocompatible and adaptable envelope, and pair-operated ultrasonic sensors for restenosis monitoring through flow velocity. Aside from continuous monitoring of restenosis post-implantation, it is also important to evaluate whether the stent design itself causes complications such as restenosis or thrombosis. Therefore, computational fluid dynamic (CFD) analysis before and after stent implantation were carried out as well as finite element analysis (FEA). The proposed smart stent was put in the descending thoracic section of a virtually reconstructed aorta that comes from a computed tomography (CT) scan. Blood flow velocity showed that after stent implantation, there is not liquid retention or vortex generation. In addition, blood pressures after stent implantation were within the normal blood pressure values. The stress and the factor of safety (FOS) analysis showed that the stress values reached by the stent are very far from the yield strength limit of the materials and that the stent is stiff enough to support the applied loads exported from the CFD results.
published_date	2020-11-24T04:22:10Z
_version_	1763754461179674624
score	10.969907

A Smart Stent for Monitoring Eventual Restenosis: Computational Fluid Dynamic and Finite Element Analysis in Descending Thoracic Aorta

Similar Items