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Glycemia Around Exercise in Adults with Type 1 Diabetes Using Automated and Nonautomated Insulin Delivery Pumps: A Switch Pilot Trial

Olivia M. McCarthy Orcid Logo, Merete Bechmann Christensen, Kasper Birch Kristensen, Signe Schmidt Orcid Logo, Ajenthen G. Ranjan, Stephen C. Bain, Richard Bracken Orcid Logo, Kirsten Nørgaard

Diabetes Technology & Therapeutics, Volume: 25, Issue: 4, Pages: 287 - 292

Swansea University Author: Richard Bracken Orcid Logo

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DOI (Published version): 10.1089/dia.2022.0542

Abstract

In an in-patient switch study, 10 adults with type 1 diabetes (T1D) performed 45 min of moderate-intensity exercise on 2 occasions: (1) when using their usual insulin pump (UP) and (2) after transitioning to automated insulin delivery (AID) treatment (MiniMed™ 780G). Consensus glucose management gui...

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Published in: Diabetes Technology & Therapeutics
ISSN: 1520-9156 1557-8593
Published: Mary Ann Liebert Inc 2023
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URI: https://cronfa.swan.ac.uk/Record/cronfa63164
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spelling 2024-05-15T15:16:56.6304852 v2 63164 2023-04-17 Glycemia Around Exercise in Adults with Type 1 Diabetes Using Automated and Nonautomated Insulin Delivery Pumps: A Switch Pilot Trial f5da81cd18adfdedb2ccb845bddc12f7 0000-0002-6986-6449 Richard Bracken Richard Bracken true false 2023-04-17 EAAS In an in-patient switch study, 10 adults with type 1 diabetes (T1D) performed 45 min of moderate-intensity exercise on 2 occasions: (1) when using their usual insulin pump (UP) and (2) after transitioning to automated insulin delivery (AID) treatment (MiniMed™ 780G). Consensus glucose management guidelines for performing exercise were applied. Plasma glucose concentrations measured over a 3-h monitoring period were stratified into time below range (TBR, <3.9 mmol/L), time in range (TIR, 3.9–10.0 mmol/L), and time above range (TAR, >10.0 mmol/L).Overall, TBR (UP: 11 ± 21 vs. AID: 3% ± 10%, P = 0.413), TIR (UP: 53 ± 27 vs. AID: 66% ± 39%, P = 0.320), and TAR (UP: 37 ± 34 vs. AID: 31% ± 41%, P = 0.604) were similar between arms. A proportionately low number of people experienced exercise-induced hypoglycemia (UP: n = 2 vs. AID: n = 1, P = 1.00).In conclusion, switching to AID therapy did not alter patterns of glycemia around sustained moderate-intensity exercise in adults with T1D. Journal Article Diabetes Technology & Therapeutics 25 4 287 292 Mary Ann Liebert Inc 1520-9156 1557-8593 1 4 2023 2023-04-01 10.1089/dia.2022.0542 http://dx.doi.org/10.1089/dia.2022.0542 COLLEGE NANME Engineering and Applied Sciences School COLLEGE CODE EAAS Swansea University 2024-05-15T15:16:56.6304852 2023-04-17T09:32:55.0508816 Faculty of Science and Engineering School of Engineering and Applied Sciences - Sport and Exercise Sciences Olivia M. McCarthy 0000-0001-6971-611x 1 Merete Bechmann Christensen 2 Kasper Birch Kristensen 3 Signe Schmidt 0000-0002-6968-6675 4 Ajenthen G. Ranjan 5 Stephen C. Bain 6 Richard Bracken 0000-0002-6986-6449 7 Kirsten Nørgaard 8 63164__27136__c8d44358d18d4364a57fa58716e3f6d6.pdf 63164.pdf 2023-04-20T08:14:07.9999929 Output 326819 application/pdf Accepted Manuscript true true eng
title Glycemia Around Exercise in Adults with Type 1 Diabetes Using Automated and Nonautomated Insulin Delivery Pumps: A Switch Pilot Trial
spellingShingle Glycemia Around Exercise in Adults with Type 1 Diabetes Using Automated and Nonautomated Insulin Delivery Pumps: A Switch Pilot Trial
Richard Bracken
title_short Glycemia Around Exercise in Adults with Type 1 Diabetes Using Automated and Nonautomated Insulin Delivery Pumps: A Switch Pilot Trial
title_full Glycemia Around Exercise in Adults with Type 1 Diabetes Using Automated and Nonautomated Insulin Delivery Pumps: A Switch Pilot Trial
title_fullStr Glycemia Around Exercise in Adults with Type 1 Diabetes Using Automated and Nonautomated Insulin Delivery Pumps: A Switch Pilot Trial
title_full_unstemmed Glycemia Around Exercise in Adults with Type 1 Diabetes Using Automated and Nonautomated Insulin Delivery Pumps: A Switch Pilot Trial
title_sort Glycemia Around Exercise in Adults with Type 1 Diabetes Using Automated and Nonautomated Insulin Delivery Pumps: A Switch Pilot Trial
author_id_str_mv f5da81cd18adfdedb2ccb845bddc12f7
author_id_fullname_str_mv f5da81cd18adfdedb2ccb845bddc12f7_***_Richard Bracken
author Richard Bracken
author2 Olivia M. McCarthy
Merete Bechmann Christensen
Kasper Birch Kristensen
Signe Schmidt
Ajenthen G. Ranjan
Stephen C. Bain
Richard Bracken
Kirsten Nørgaard
format Journal article
container_title Diabetes Technology & Therapeutics
container_volume 25
container_issue 4
container_start_page 287
publishDate 2023
institution Swansea University
issn 1520-9156
1557-8593
doi_str_mv 10.1089/dia.2022.0542
publisher Mary Ann Liebert Inc
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Engineering and Applied Sciences - Sport and Exercise Sciences{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Sport and Exercise Sciences
url http://dx.doi.org/10.1089/dia.2022.0542
document_store_str 1
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description In an in-patient switch study, 10 adults with type 1 diabetes (T1D) performed 45 min of moderate-intensity exercise on 2 occasions: (1) when using their usual insulin pump (UP) and (2) after transitioning to automated insulin delivery (AID) treatment (MiniMed™ 780G). Consensus glucose management guidelines for performing exercise were applied. Plasma glucose concentrations measured over a 3-h monitoring period were stratified into time below range (TBR, <3.9 mmol/L), time in range (TIR, 3.9–10.0 mmol/L), and time above range (TAR, >10.0 mmol/L).Overall, TBR (UP: 11 ± 21 vs. AID: 3% ± 10%, P = 0.413), TIR (UP: 53 ± 27 vs. AID: 66% ± 39%, P = 0.320), and TAR (UP: 37 ± 34 vs. AID: 31% ± 41%, P = 0.604) were similar between arms. A proportionately low number of people experienced exercise-induced hypoglycemia (UP: n = 2 vs. AID: n = 1, P = 1.00).In conclusion, switching to AID therapy did not alter patterns of glycemia around sustained moderate-intensity exercise in adults with T1D.
published_date 2023-04-01T08:15:44Z
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