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Trends in SARS-CoV-2 infection and vaccination in school staff, students and their household members from 2020 to 2022 in Wales, UK: an electronic cohort study

Emily Lowthian Orcid Logo, Hoda Abbasizanjani Orcid Logo, Stuart Bedston, Ashley Akbari Orcid Logo, Laura Cowley, Rich Fry Orcid Logo, Rhiannon Owen Orcid Logo, Joseph Hollinghurst, Igor Rudan, Jillian Beggs, Emily Marchant Orcid Logo, Fatemeh Torabi Orcid Logo, Simon de Lusignan, Tom Crick Orcid Logo, Graham Moore, Aziz Sheikh, Ronan Lyons Orcid Logo

Journal of the Royal Society of Medicine, Volume: 116, Issue: 12, Pages: 413 - 424

Swansea University Authors: Emily Lowthian Orcid Logo, Hoda Abbasizanjani Orcid Logo, Stuart Bedston, Ashley Akbari Orcid Logo, Laura Cowley, Rich Fry Orcid Logo, Rhiannon Owen Orcid Logo, Joseph Hollinghurst, Emily Marchant Orcid Logo, Fatemeh Torabi Orcid Logo, Tom Crick Orcid Logo, Ronan Lyons Orcid Logo

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Abstract

Objectives: We investigated SARS-CoV-2 infection trends, risk of SARS-CoV-2 infection and COVID-19 vaccination uptake among school staff, students and their household members in Wales, UK.Design: Seven-day average of SARS-CoV-2 infections and polymerase chain reaction tests per 1000 people daily, cu...

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Published in: Journal of the Royal Society of Medicine
ISSN: 0141-0768 1758-1095
Published: SAGE Publications 2023
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa63604
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Abstract: Objectives: We investigated SARS-CoV-2 infection trends, risk of SARS-CoV-2 infection and COVID-19 vaccination uptake among school staff, students and their household members in Wales, UK.Design: Seven-day average of SARS-CoV-2 infections and polymerase chain reaction tests per 1000 people daily, cumulative incidence of COVID-19 vaccination uptake and multi-level Poisson models with time-varying covariates. Setting: National electronic cohort between September 2020 and May 2022 when several variants were predominant in the UK (Alpha, Delta and Omicron). Participants: School students aged 4 to 10/11 years (primary school and younger middle school, n = 238,163), and 11 to 15/16 years (secondary school and older middle school, n = 182,775), school staff in Wales (n = 47,963) and the household members of students and staff (n = 697,659). Main outcome measures: SARS-CoV-2 infection and COVID-19 vaccination uptake.
Keywords: COVID-19, pandemic, population health, schools, social restrictions
College: Faculty of Medicine, Health and Life Sciences
Funders: This work was supported by the Con-COV team funded by the Medical Research Council (grant number: MR/V028367/1). This work was supported by Health Data Research UK, which receives its funding from HDR UK Ltd (HDR-9006) funded by the UK Medical Research Council, Engineering and Physical Sciences Research Council, Economic and Social Research Council, Department of Health and Social Care (England), Chief Scientist Office of the Scottish Government Health and Social Care Directorates, Health and Social Care Research and Development Division (Welsh Government), Public Health Agency (Northern Ireland), British Heart Foundation (BHF) and the Wellcome Trust. This work was supported by the ADR Wales programme of work. The ADR Wales programme of work is aligned to the priority themes as identified in the Welsh Government’s national strategy: Prosperity for All. ADR Wales brings together data science experts at Swansea University Medical School, staff from the Wales Institute of Social and Economic Research, Data and Methods at Cardiff University and specialist teams within the Welsh Government to develop new evidence which supports Prosperity for All by using the SAIL Databank at Swansea University to link and analyse anonymised data. ADR Wales is part of the Economic and Social Research Council (part of UK Research and Innovation) funded ADR UK (grant ES/W012227/1). This work was supported by the Wales COVID-19 Evidence Centre, funded by Health and Care Research Wales. RKO is supported by the Academy of Medical Sciences/the Wellcome Trust/the Government Department of Business, Energy and Industrial Strategy/the British Heart Foundation/Diabetes UK Springboard Award (SBF006\1122).
Issue: 12
Start Page: 413
End Page: 424