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Role of herbs at the crossroads of metabolic syndrome and mental illness

Sanjib Chakraborty, Subhasri Bogadi, Divya Pamu, Veera Venkata Satyanarayana Reddy Karri, Anthony Booker, Vivian Rolfe, Suresh Mohankumar Orcid Logo

Indian Journal of Biochemistry and Biophysics, Volume: 60, Issue: 2

Swansea University Author: Suresh Mohankumar Orcid Logo

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DOI (Published version): 10.56042/ijbb.v60i2.70738

Abstract

The potential use of herbs in treating and managing comorbidities is emerging. Mental illnesses (MIs) are a widespread cause of distress and dysfunction and substantially impact one's quality of life. While the precise reason for the onset of mental illness is elusive, several chronic health co...

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Published in: Indian Journal of Biochemistry and Biophysics
ISSN: 0301-1208 0975-0959
Published: CSIR-National Institute of Science Communication and Policy Research (NIScPR) 2023
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URI: https://cronfa.swan.ac.uk/Record/cronfa63684
first_indexed 2023-06-22T08:54:27Z
last_indexed 2025-06-13T07:40:21Z
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spelling 2025-06-11T13:31:17.6306874 v2 63684 2023-06-22 Role of herbs at the crossroads of metabolic syndrome and mental illness edce0da45e3933d3460963b966f4c84e 0000-0001-8862-2979 Suresh Mohankumar Suresh Mohankumar true false 2023-06-22 MEDS The potential use of herbs in treating and managing comorbidities is emerging. Mental illnesses (MIs) are a widespread cause of distress and dysfunction and substantially impact one's quality of life. While the precise reason for the onset of mental illness is elusive, several chronic health complications, including metabolic syndrome (MetS), affect an individual's well-being. Thus, it is beneficial to identify the intercepts and explore the role of herbs in combating MetS-associated MIs or vice versa. This study explores the relationship between Mets and mental illness and assesses which herbs may have properties that benefit both conditions. The research design and selection process were done among the mental disorder individuals with two sets of keywords and expanded controlled vocabulary phrases, nine databases for systematic literature searches, critical assessment of the papers obtained, and meta-analysis. Our findings suggest that the excess levels of inflammatory cytokines such as C-reactive protein, interleukin, and leptin resistance in MetS strongly correlate with MIs such as depression. The resulting cross-sectional pooled odds ratio was 1.75 (95% CI 1.60-1.92), indicating a strong relationship between Mets and MIs. This study provides an essential theoretical foundation for therapeutic options and prospective intervention methods for comorbid Mets and mental illness. Some herbs have a relevant effect in treating both cases, broadening the breadth of knowledge to guide future research on this topic. Journal Article Indian Journal of Biochemistry and Biophysics 60 2 CSIR-National Institute of Science Communication and Policy Research (NIScPR) 0301-1208 0975-0959 Herbs, Mental illness, Metabolic disorders, Mets 1 2 2023 2023-02-01 10.56042/ijbb.v60i2.70738 COLLEGE NANME Medical School COLLEGE CODE MEDS Swansea University Not Required 2025-06-11T13:31:17.6306874 2023-06-22T09:50:33.8240625 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Pharmacy Sanjib Chakraborty 1 Subhasri Bogadi 2 Divya Pamu 3 Veera Venkata Satyanarayana Reddy Karri 4 Anthony Booker 5 Vivian Rolfe 6 Suresh Mohankumar 0000-0001-8862-2979 7 63684__28108__399c0d8d4ad7434a8f7126c09c689768.pdf 63684.pdf 2023-07-12T16:57:53.8774327 Output 948053 application/pdf Version of Record true Licensed under a Creative Commons Attribution-BY-NC-ND 4.0 International License. true eng http://creativecommons.org/licenses/by-nc-nd/4.0/
title Role of herbs at the crossroads of metabolic syndrome and mental illness
spellingShingle Role of herbs at the crossroads of metabolic syndrome and mental illness
Suresh Mohankumar
title_short Role of herbs at the crossroads of metabolic syndrome and mental illness
title_full Role of herbs at the crossroads of metabolic syndrome and mental illness
title_fullStr Role of herbs at the crossroads of metabolic syndrome and mental illness
title_full_unstemmed Role of herbs at the crossroads of metabolic syndrome and mental illness
title_sort Role of herbs at the crossroads of metabolic syndrome and mental illness
author_id_str_mv edce0da45e3933d3460963b966f4c84e
author_id_fullname_str_mv edce0da45e3933d3460963b966f4c84e_***_Suresh Mohankumar
author Suresh Mohankumar
author2 Sanjib Chakraborty
Subhasri Bogadi
Divya Pamu
Veera Venkata Satyanarayana Reddy Karri
Anthony Booker
Vivian Rolfe
Suresh Mohankumar
format Journal article
container_title Indian Journal of Biochemistry and Biophysics
container_volume 60
container_issue 2
publishDate 2023
institution Swansea University
issn 0301-1208
0975-0959
doi_str_mv 10.56042/ijbb.v60i2.70738
publisher CSIR-National Institute of Science Communication and Policy Research (NIScPR)
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Pharmacy{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Pharmacy
document_store_str 1
active_str 0
description The potential use of herbs in treating and managing comorbidities is emerging. Mental illnesses (MIs) are a widespread cause of distress and dysfunction and substantially impact one's quality of life. While the precise reason for the onset of mental illness is elusive, several chronic health complications, including metabolic syndrome (MetS), affect an individual's well-being. Thus, it is beneficial to identify the intercepts and explore the role of herbs in combating MetS-associated MIs or vice versa. This study explores the relationship between Mets and mental illness and assesses which herbs may have properties that benefit both conditions. The research design and selection process were done among the mental disorder individuals with two sets of keywords and expanded controlled vocabulary phrases, nine databases for systematic literature searches, critical assessment of the papers obtained, and meta-analysis. Our findings suggest that the excess levels of inflammatory cytokines such as C-reactive protein, interleukin, and leptin resistance in MetS strongly correlate with MIs such as depression. The resulting cross-sectional pooled odds ratio was 1.75 (95% CI 1.60-1.92), indicating a strong relationship between Mets and MIs. This study provides an essential theoretical foundation for therapeutic options and prospective intervention methods for comorbid Mets and mental illness. Some herbs have a relevant effect in treating both cases, broadening the breadth of knowledge to guide future research on this topic.
published_date 2023-02-01T05:12:18Z
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