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A study evaluating quality of life and factors affecting it before, during and after menopause

Hayley Hutchings Orcid Logo, Nia Taylor, ANAGHA REMESH, Jim Rafferty Orcid Logo

European Journal of Obstetrics & Gynecology and Reproductive Biology, Volume: 289, Pages: 100 - 107

Swansea University Authors: Hayley Hutchings Orcid Logo, ANAGHA REMESH, Jim Rafferty Orcid Logo

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Abstract

Objective: To determine if quality of life (QoL) changes before, during and after menopause and whether these changes are linked to symptoms, demographics, and/or lifestyle factors. Methods: We undertook a cross-sectional online survey. We invited women aged between 35 and 60 years to complete the s...

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Published in: European Journal of Obstetrics & Gynecology and Reproductive Biology
ISSN: 0301-2115 1872-7654
Published: Elsevier BV 2023
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa64128
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Abstract: Objective: To determine if quality of life (QoL) changes before, during and after menopause and whether these changes are linked to symptoms, demographics, and/or lifestyle factors. Methods: We undertook a cross-sectional online survey. We invited women aged between 35 and 60 years to complete the survey which included the Short-Form 36 (SF-36) generic quality of life measure, the menopause specific Utian-Quality of life (UQOL) measure, and questions about health and wellbeing, menopause symptoms and hormonal stage. The data were analysed with one-way ANOVA analysis and multivariate regression modelling. Results: 279 women completed the survey. Most were aged between 51 and 55 years. In the unadjusted analysis there was a tendency for QoL to deteriorate from pre to peri to menopause and then increase slightly post menopause. This was however not significant in multivariate analysis. Multivariate analysis identified that lifestyle factors significantly influenced QoL. Regular exercise resulted in better QoL scores across a number of the UQol and SF-36 sub-scales. Being very overweight and having more menopause symptoms resulted in worse QoL. Conclusions: Although there was a trend towards worse quality of life in the peri and menopause stages this was not significantly different in adjusted multivariate analyses. Those experiencing more symptoms had significantly worse QoL. Lifestyle factors may affect QoL, but the picture is not straightforward. It is promising that there was a trend toward improved QoL in the post-menopausal stage. These findings should inform education material and promote awareness of the menopause and its impact on QoL.
Keywords: Menopause, Quality of life, Patient reported outcome measures, SF-36, UQOL
College: Faculty of Medicine, Health and Life Sciences
Funders: Swansea University
Start Page: 100
End Page: 107