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Synthesis and chemiluminescent characteristics of two new acridinium esters

Keith Smith, Xiaojing Mu Orcid Logo, Zhaoqiang Li, J. Stuart Woodhead, Gamal A. El‐Hiti Orcid Logo

Luminescence

Swansea University Authors: Keith Smith, Xiaojing Mu Orcid Logo

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DOI (Published version): 10.1002/bio.4572

Abstract

Two new acridinium esters with a 2-(succinimidyloxycarbonyl)ethyl side arm, namely, 9-(2,6-dibromophenoxycarbonyl)-10-methyl-2-(2-(succinimidyloxycarbonyl)ethyl)acridinium trifluoromethanesulfonate and 9-(4-(2-(succinimidyloxycarbonyl)ethyl)phenoxycarbonyl)-2,7-dimethoxy-10-methylacridinium triflate...

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Published in: Luminescence
ISSN: 1522-7235 1522-7243
Published: Wiley 2023
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa64365
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Abstract: Two new acridinium esters with a 2-(succinimidyloxycarbonyl)ethyl side arm, namely, 9-(2,6-dibromophenoxycarbonyl)-10-methyl-2-(2-(succinimidyloxycarbonyl)ethyl)acridinium trifluoromethanesulfonate and 9-(4-(2-(succinimidyloxycarbonyl)ethyl)phenoxycarbonyl)-2,7-dimethoxy-10-methylacridinium triflate, have been produced and characterized. The chemiluminescent properties and hydrolytic stabilities of the new acridinium esters have been investigated.
Keywords: Acridinium ester, chemiluminescence, hydrolysis, linker arm, side arm, stability
College: Faculty of Science and Engineering
Funders: Chinese Government Scholarship, Molecular Light Technology Research Limited, Cardiff, UK, UK Government for an Overseas Research Studentship, King Saud University (Grant Number: RSP2023R404)

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