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Responsible use of negative research outcomes—accelerating the discovery and development of new antibiotics

Helen Yu

The Journal of Antibiotics, Volume: 74, Issue: 9, Pages: 543 - 546

Swansea University Author: Helen Yu

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DOI (Published version): 10.1038/s41429-021-00439-w

Abstract

Failure to share and make use of existing knowledge, particularly negative research outcomes, has been recognized as one of the key sources of waste and inefficiency in the drug discovery and development process. In the field of antibiotic research, providing a platform where negative outcomes could...

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Published in: The Journal of Antibiotics
ISSN: 0021-8820 1881-1469
Published: Springer Science and Business Media LLC 2021
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URI: https://cronfa.swan.ac.uk/Record/cronfa64382
Abstract: Failure to share and make use of existing knowledge, particularly negative research outcomes, has been recognized as one of the key sources of waste and inefficiency in the drug discovery and development process. In the field of antibiotic research, providing a platform where negative outcomes could be shared to prevent the vicious cycle of duplicating costly studies that produce the same negative results would greatly de-risk and accelerate the development of new antibiotics. Providing a legally supported framework that recognizes negative outcomes as intellectual contributions, which can subsequently be translated into a revenue-sharing model, may lead to more openness and value creation in support of a sustainable and responsible transformation of research into socially and economically beneficial innovations.
Keywords: Negative research outcomes, drug discovery, drug development, antibiotic research
College: Faculty of Humanities and Social Sciences
Funders: This research is supported by a grant from the Center for Digital Life Norway and the Research Council of Norway (grant agreement number 294594) and by a Novo Nordisk Foundation grant for a scientifically independent Collaborative Research Program for Biomedical Innovation Law (grant agreement number NNF17SA0027784).
Issue: 9
Start Page: 543
End Page: 546

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