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Global well-posedness and nonlinear stability of a chemotaxis system modelling multiple sclerosis

Laurent Desvillettes, Valeria Giunta Orcid Logo, Jeff Morgan, Bao Quoc Tang

Proceedings of the Royal Society of Edinburgh: Section A Mathematics, Volume: 152, Issue: 4, Pages: 826 - 856

Swansea University Author: Valeria Giunta Orcid Logo

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DOI (Published version): 10.1017/prm.2021.33

Abstract

We consider a system of reaction–diffusion equations including chemotaxis terms and coming out of the modelling of multiple sclerosis. The global existence of strong solutions to this system in any dimension is proved, and it is also shown that the solution is bounded uniformly in time. Finally, a n...

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Published in: Proceedings of the Royal Society of Edinburgh: Section A Mathematics
ISSN: 0308-2105 1473-7124
Published: Cambridge University Press (CUP) 2022
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URI: https://cronfa.swan.ac.uk/Record/cronfa64700
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Abstract: We consider a system of reaction–diffusion equations including chemotaxis terms and coming out of the modelling of multiple sclerosis. The global existence of strong solutions to this system in any dimension is proved, and it is also shown that the solution is bounded uniformly in time. Finally, a nonlinear stability result is obtained when the chemotaxis term is not too big. We also perform numerical simulations to show the appearance of Turing patterns when the chemotaxis term is large.
Keywords: Chemotaxis models, Global solutions, Uniform-in-time bounds, Nonlinear stability, Cross diffusion
College: Faculty of Science and Engineering
Issue: 4
Start Page: 826
End Page: 856