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Non-ionic small amphiphile based nanostructures for biomedical applications

Badri Parshad, Suchita Prasad, Sumati Bhatia Orcid Logo, Ayushi Mittal, Yuanwei Pan, Prashant Kumar Mishra, Sunil K. Sharma Orcid Logo, Ljiljana Fruk Orcid Logo

RSC Advances, Volume: 10, Issue: 69, Pages: 42098 - 42115

Swansea University Author: Sumati Bhatia Orcid Logo

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DOI (Published version): 10.1039/d0ra08092f

Abstract

Self-assembly of non-ionic amphiphilic architectures into nanostructures with defined size, shape and morphology has garnered substantial momentum in the recent years due to their extensive applications in biomedicine. The manifestation of a wide range of morphologies such as micelles, vesicles, fib...

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Published in: RSC Advances
ISSN: 2046-2069
Published: Royal Society of Chemistry (RSC) 2020
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa64868
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Abstract: Self-assembly of non-ionic amphiphilic architectures into nanostructures with defined size, shape and morphology has garnered substantial momentum in the recent years due to their extensive applications in biomedicine. The manifestation of a wide range of morphologies such as micelles, vesicles, fibers, tubes, and toroids is thought to be related to the structure of amphiphilic architectures, in particular, the choice of the hydrophilic and hydrophobic parts. In this review, we look at different types of non-ionic small amphiphilic architectures and the factors that influence their self-assembly into various nanostructures in aqueous medium. In particular, we focus on the explored structural parameters that guide the formation of various nanostructures, and the ways these structures can be used in applications ranging from drug delivery to cell imaging.
Keywords: Amphiphiles, non-ionic amphiphilic architectures, nanostructures, biomedicine, biomedical applications
College: Faculty of Science and Engineering
Funders: B. P. is funded by Cancer research UK Primer Award (C67674/A27887). We acknowledge UGC-CSIR, New Delhi, for providing fellowship to A. M.
Issue: 69
Start Page: 42098
End Page: 42115