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Molecular insights into high-altitude adaption and acclimatisation of Aporrectodea caliginosa

Iain Perry Orcid Logo, Szabolcs Balazs Hernadi, Luis Cunha Orcid Logo, Stephen Short, Angela Marchbank, David J Spurgeon Orcid Logo, Pablo Orozco-terWengel Orcid Logo, Peter Kille

Life Science Alliance, Volume: 5, Issue: 11, Start page: e202201513

Swansea University Author: Iain Perry Orcid Logo

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DOI (Published version): 10.26508/lsa.202201513

Abstract

Here, we explore the high-altitude adaptions and acclimatisation of Aporrectodea caliginosa. Population diversity is assessed through mitochondrial barcoding, identifying closely related populations across the island of Pico (Azores). We present the first megabase N50 assembly size (1.2 Mbp) genome...

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Published in: Life Science Alliance
ISSN: 2575-1077
Published: Life Science Alliance, LLC 2022
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URI: https://cronfa.swan.ac.uk/Record/cronfa65667
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spelling v2 65667 2024-02-22 Molecular insights into high-altitude adaption and acclimatisation of Aporrectodea caliginosa 7d630cc1fa34fdcd873711c80a874322 0000-0001-8530-4086 Iain Perry Iain Perry true false 2024-02-22 BMS Here, we explore the high-altitude adaptions and acclimatisation of Aporrectodea caliginosa. Population diversity is assessed through mitochondrial barcoding, identifying closely related populations across the island of Pico (Azores). We present the first megabase N50 assembly size (1.2 Mbp) genome for A. caliginosa. High- and low-altitude populations were exposed experimentally to a range of oxygen and temperature conditions, simulating altitudinal conditions, and the transcriptomic responses explored. SNP densities are assessed to identify signatures of selective pressure and their link to differentially expressed genes. The high-altitude A. caliginosa population had lower differential expression and fewer co-expressed genes between conditions, indicating a more condition-refined epigenetic response. Genes identified as under adaptive pressure through Fst and nucleotide diversity in the high-altitude population clustered around the differentially expressed an upstream environmental response control gene, HMGB1. The high-altitude population of A. caliginosa indicated adaption and acclimatisation to high-altitude conditions and suggested resilience to extreme weather events. This mechanistic understanding could help offer a strategy in further identifying other species capable of maintaining soil fertility in extreme environments. Journal Article Life Science Alliance 5 11 e202201513 Life Science Alliance, LLC 2575-1077 17 8 2022 2022-08-17 10.26508/lsa.202201513 COLLEGE NANME Biomedical Sciences COLLEGE CODE BMS Swansea University Another institution paid the OA fee Natural Environment Research Council (NE/R016429/1) 2024-03-26T13:46:05.5375483 2024-02-22T14:52:54.8376616 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Biomedical Science Iain Perry 0000-0001-8530-4086 1 Szabolcs Balazs Hernadi 2 Luis Cunha 0000-0002-5870-2537 3 Stephen Short 4 Angela Marchbank 5 David J Spurgeon 0000-0003-3264-8760 6 Pablo Orozco-terWengel 0000-0002-7951-4148 7 Peter Kille 8 65667__29854__f1e0686c9cb64f3d87da75e11f5d3e3a.pdf 65667.VOR.pdf 2024-03-26T13:36:34.5732625 Output 2592115 application/pdf Version of Record true This article is available under a Creative Commons Attribution 4.0 Internationa license. true eng https://creativecommons.org/licenses/by/4.0/
title Molecular insights into high-altitude adaption and acclimatisation of Aporrectodea caliginosa
spellingShingle Molecular insights into high-altitude adaption and acclimatisation of Aporrectodea caliginosa
Iain Perry
title_short Molecular insights into high-altitude adaption and acclimatisation of Aporrectodea caliginosa
title_full Molecular insights into high-altitude adaption and acclimatisation of Aporrectodea caliginosa
title_fullStr Molecular insights into high-altitude adaption and acclimatisation of Aporrectodea caliginosa
title_full_unstemmed Molecular insights into high-altitude adaption and acclimatisation of Aporrectodea caliginosa
title_sort Molecular insights into high-altitude adaption and acclimatisation of Aporrectodea caliginosa
author_id_str_mv 7d630cc1fa34fdcd873711c80a874322
author_id_fullname_str_mv 7d630cc1fa34fdcd873711c80a874322_***_Iain Perry
author Iain Perry
author2 Iain Perry
Szabolcs Balazs Hernadi
Luis Cunha
Stephen Short
Angela Marchbank
David J Spurgeon
Pablo Orozco-terWengel
Peter Kille
format Journal article
container_title Life Science Alliance
container_volume 5
container_issue 11
container_start_page e202201513
publishDate 2022
institution Swansea University
issn 2575-1077
doi_str_mv 10.26508/lsa.202201513
publisher Life Science Alliance, LLC
college_str Faculty of Medicine, Health and Life Sciences
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hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Biomedical Science{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Biomedical Science
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description Here, we explore the high-altitude adaptions and acclimatisation of Aporrectodea caliginosa. Population diversity is assessed through mitochondrial barcoding, identifying closely related populations across the island of Pico (Azores). We present the first megabase N50 assembly size (1.2 Mbp) genome for A. caliginosa. High- and low-altitude populations were exposed experimentally to a range of oxygen and temperature conditions, simulating altitudinal conditions, and the transcriptomic responses explored. SNP densities are assessed to identify signatures of selective pressure and their link to differentially expressed genes. The high-altitude A. caliginosa population had lower differential expression and fewer co-expressed genes between conditions, indicating a more condition-refined epigenetic response. Genes identified as under adaptive pressure through Fst and nucleotide diversity in the high-altitude population clustered around the differentially expressed an upstream environmental response control gene, HMGB1. The high-altitude population of A. caliginosa indicated adaption and acclimatisation to high-altitude conditions and suggested resilience to extreme weather events. This mechanistic understanding could help offer a strategy in further identifying other species capable of maintaining soil fertility in extreme environments.
published_date 2022-08-17T13:46:02Z
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