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MS care: integrating advanced therapies and holistic management

Gavin Giovannoni, Helen L. Ford, Klaus Schmierer, Rod Middleton Orcid Logo, Andrea M. Stennett, Ian Pomeroy, Leonora Fisniku, Antonio Scalfari, Colin Bannon, Ruth Stross, Sarah Hughes, Adam Williams, Samantha Josephs, Charlie Peel, Agne Straukiene

Frontiers in Neurology, Volume: 14, Start page: 1286122

Swansea University Author: Rod Middleton Orcid Logo

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    © 2024 Giovannoni, Ford, Schmierer, Middleton, Stennett, Pomeroy, Fisniku, Scalfari, Bannon, Stross, Hughes, Williams, Josephs, Peel and Straukiene. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).

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DOI (Published version): 10.3389/fneur.2023.1286122

Abstract

Lifestyle and environmental factors are key determinants in disease causality and progression in neurological conditions, including multiple sclerosis (MS). Lack of exercise, poor diet, tobacco smoking, excessive alcohol intake, social determinants of health, concomitant medications, poor sleep and...

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Published in: Frontiers in Neurology
ISSN: 1664-2295
Published: Frontiers Media SA 2024
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URI: https://cronfa.swan.ac.uk/Record/cronfa68039
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last_indexed 2025-02-13T05:44:57Z
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Lack of exercise, poor diet, tobacco smoking, excessive alcohol intake, social determinants of health, concomitant medications, poor sleep and comorbidities can exacerbate MS pathological processes by impacting brain health and depleting neurological reserves, resulting in more rapid disease worsening. In addition to using disease-modifying therapies to alter the disease course, therapeutic strategies in MS should aim to preserve as much neurological reserve as possible by promoting the adoption of a &#x201C;brain-healthy&#x201D; and &#x201C;metabolically-healthy&#x201D; lifestyle. Here, we recommend self-regulated lifestyle modifications that have the potential to improve brain health, directly impact on disease progression and improve outcomes in people with MS. 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spelling 2025-02-12T15:30:40.6934585 v2 68039 2024-10-22 MS care: integrating advanced therapies and holistic management 005518f819ef1a2a13fdf438529bdfcd 0000-0002-2130-4420 Rod Middleton Rod Middleton true false 2024-10-22 MEDS Lifestyle and environmental factors are key determinants in disease causality and progression in neurological conditions, including multiple sclerosis (MS). Lack of exercise, poor diet, tobacco smoking, excessive alcohol intake, social determinants of health, concomitant medications, poor sleep and comorbidities can exacerbate MS pathological processes by impacting brain health and depleting neurological reserves, resulting in more rapid disease worsening. In addition to using disease-modifying therapies to alter the disease course, therapeutic strategies in MS should aim to preserve as much neurological reserve as possible by promoting the adoption of a “brain-healthy” and “metabolically-healthy” lifestyle. Here, we recommend self-regulated lifestyle modifications that have the potential to improve brain health, directly impact on disease progression and improve outcomes in people with MS. We emphasise the importance of self-management and adopting a multidisciplinary, collaborative and person-centred approach to care that encompasses the healthcare team, family members and community support groups. Journal Article Frontiers in Neurology 14 1286122 Frontiers Media SA 1664-2295 multiple sclerosis, brain health, lifestyle, disease progression, outcomes, holistic care, recommendations 30 1 2024 2024-01-30 10.3389/fneur.2023.1286122 Review article COLLEGE NANME Medical School COLLEGE CODE MEDS Swansea University Another institution paid the OA fee Biogen 2025-02-12T15:30:40.6934585 2024-10-22T13:27:32.5391410 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Health Data Science Gavin Giovannoni 1 Helen L. Ford 2 Klaus Schmierer 3 Rod Middleton 0000-0002-2130-4420 4 Andrea M. Stennett 5 Ian Pomeroy 6 Leonora Fisniku 7 Antonio Scalfari 8 Colin Bannon 9 Ruth Stross 10 Sarah Hughes 11 Adam Williams 12 Samantha Josephs 13 Charlie Peel 14 Agne Straukiene 15 68039__33215__358aaadba47f40e283d6c831f7c719fc.pdf 68039.VoR.pdf 2024-12-20T14:04:32.8843767 Output 3746535 application/pdf Version of Record true © 2024 Giovannoni, Ford, Schmierer, Middleton, Stennett, Pomeroy, Fisniku, Scalfari, Bannon, Stross, Hughes, Williams, Josephs, Peel and Straukiene. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). true eng http://creativecommons.org/licenses/by/4.0/
title MS care: integrating advanced therapies and holistic management
spellingShingle MS care: integrating advanced therapies and holistic management
Rod Middleton
title_short MS care: integrating advanced therapies and holistic management
title_full MS care: integrating advanced therapies and holistic management
title_fullStr MS care: integrating advanced therapies and holistic management
title_full_unstemmed MS care: integrating advanced therapies and holistic management
title_sort MS care: integrating advanced therapies and holistic management
author_id_str_mv 005518f819ef1a2a13fdf438529bdfcd
author_id_fullname_str_mv 005518f819ef1a2a13fdf438529bdfcd_***_Rod Middleton
author Rod Middleton
author2 Gavin Giovannoni
Helen L. Ford
Klaus Schmierer
Rod Middleton
Andrea M. Stennett
Ian Pomeroy
Leonora Fisniku
Antonio Scalfari
Colin Bannon
Ruth Stross
Sarah Hughes
Adam Williams
Samantha Josephs
Charlie Peel
Agne Straukiene
format Journal article
container_title Frontiers in Neurology
container_volume 14
container_start_page 1286122
publishDate 2024
institution Swansea University
issn 1664-2295
doi_str_mv 10.3389/fneur.2023.1286122
publisher Frontiers Media SA
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Health Data Science{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Health Data Science
document_store_str 1
active_str 0
description Lifestyle and environmental factors are key determinants in disease causality and progression in neurological conditions, including multiple sclerosis (MS). Lack of exercise, poor diet, tobacco smoking, excessive alcohol intake, social determinants of health, concomitant medications, poor sleep and comorbidities can exacerbate MS pathological processes by impacting brain health and depleting neurological reserves, resulting in more rapid disease worsening. In addition to using disease-modifying therapies to alter the disease course, therapeutic strategies in MS should aim to preserve as much neurological reserve as possible by promoting the adoption of a “brain-healthy” and “metabolically-healthy” lifestyle. Here, we recommend self-regulated lifestyle modifications that have the potential to improve brain health, directly impact on disease progression and improve outcomes in people with MS. We emphasise the importance of self-management and adopting a multidisciplinary, collaborative and person-centred approach to care that encompasses the healthcare team, family members and community support groups.
published_date 2024-01-30T05:25:35Z
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