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University education facilitates uptake of disease-modifying therapies for multiple sclerosis: A community-based study using the UK MS Register

Joyutpal Das Orcid Logo, David J Rog, Rod Middleton Orcid Logo, Jeff Rodgers, Richard Nicholas

Multiple Sclerosis Journal, Volume: 30, Issue: 2, Pages: 192 - 199

Swansea University Authors: Rod Middleton Orcid Logo, Jeff Rodgers

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DOI (Published version): 10.1177/13524585231221411

Abstract

Background: Higher education is associated with better job opportunities and higher income.Objectives: Herein, the impact of education on the uptake of disease-modifying therapies (DMTs) for multiple sclerosis (MS) in a publicly funded health care system was examined using the UK MS Register.Methods...

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Published in: Multiple Sclerosis Journal
ISSN: 1352-4585 1477-0970
Published: SAGE Publications 2024
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URI: https://cronfa.swan.ac.uk/Record/cronfa68040
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first_indexed 2024-10-22T12:33:00Z
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spelling v2 68040 2024-10-22 University education facilitates uptake of disease-modifying therapies for multiple sclerosis: A community-based study using the UK MS Register 005518f819ef1a2a13fdf438529bdfcd 0000-0002-2130-4420 Rod Middleton Rod Middleton true false 3ee27bde2acae56844ecdcbb563218ac Jeff Rodgers Jeff Rodgers true false 2024-10-22 MEDS Background: Higher education is associated with better job opportunities and higher income.Objectives: Herein, the impact of education on the uptake of disease-modifying therapies (DMTs) for multiple sclerosis (MS) in a publicly funded health care system was examined using the UK MS Register.Methods: All adult participants with relapsing remitting MS diagnosed between 2008 and 2021 were included. Those without data regarding their education levels were excluded. Binary, multinomial and Cox regression models were used to examine the association between education levels and uptake of DMTs.Results: A total of 6317 participants fulfilled all inclusion and exclusion criteria. A total of 1826/2923 (62%) participants with a university education were treated with DMTs, compared to 1788/3394 (53%) participants with school/diploma received DMTs with an odds ratio of 1.318 (1.178–1.473). Participants with a university education were more likely to be treated with both moderate- and high-efficacy DMTs, compared to others, with odds ratios of 1.227 (1.087–1.385) and 1.545 (1.325–1.802), respectively. University education was also a positive predictor for faster initiation of DMTs, and, importantly, higher-efficacy DMTs.Conclusion: In a publicly funded health care system, despite intended equality of access, university education was associated with a higher uptake of DMTs. Journal Article Multiple Sclerosis Journal 30 2 192 199 SAGE Publications 1352-4585 1477-0970 1 2 2024 2024-02-01 10.1177/13524585231221411 http://dx.doi.org/10.1177/13524585231221411 COLLEGE NANME Medical School COLLEGE CODE MEDS Swansea University Another institution paid the OA fee MS Society 2024-10-22T13:33:01.6349157 2024-10-22T13:30:44.9298175 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Health Data Science Joyutpal Das 0000-0002-9166-4624 1 David J Rog 2 Rod Middleton 0000-0002-2130-4420 3 Jeff Rodgers 4 Richard Nicholas 5 286 Rod Middleton 0000-0002-2130-4420 r.m.middleton@swansea.ac.uk false 4
title University education facilitates uptake of disease-modifying therapies for multiple sclerosis: A community-based study using the UK MS Register
spellingShingle University education facilitates uptake of disease-modifying therapies for multiple sclerosis: A community-based study using the UK MS Register
Rod Middleton
Jeff Rodgers
title_short University education facilitates uptake of disease-modifying therapies for multiple sclerosis: A community-based study using the UK MS Register
title_full University education facilitates uptake of disease-modifying therapies for multiple sclerosis: A community-based study using the UK MS Register
title_fullStr University education facilitates uptake of disease-modifying therapies for multiple sclerosis: A community-based study using the UK MS Register
title_full_unstemmed University education facilitates uptake of disease-modifying therapies for multiple sclerosis: A community-based study using the UK MS Register
title_sort University education facilitates uptake of disease-modifying therapies for multiple sclerosis: A community-based study using the UK MS Register
author_id_str_mv 005518f819ef1a2a13fdf438529bdfcd
3ee27bde2acae56844ecdcbb563218ac
author_id_fullname_str_mv 005518f819ef1a2a13fdf438529bdfcd_***_Rod Middleton
3ee27bde2acae56844ecdcbb563218ac_***_Jeff Rodgers
author Rod Middleton
Jeff Rodgers
author2 Joyutpal Das
David J Rog
Rod Middleton
Jeff Rodgers
Richard Nicholas
format Journal article
container_title Multiple Sclerosis Journal
container_volume 30
container_issue 2
container_start_page 192
publishDate 2024
institution Swansea University
issn 1352-4585
1477-0970
doi_str_mv 10.1177/13524585231221411
publisher SAGE Publications
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Health Data Science{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Health Data Science
url http://dx.doi.org/10.1177/13524585231221411
document_store_str 0
active_str 0
description Background: Higher education is associated with better job opportunities and higher income.Objectives: Herein, the impact of education on the uptake of disease-modifying therapies (DMTs) for multiple sclerosis (MS) in a publicly funded health care system was examined using the UK MS Register.Methods: All adult participants with relapsing remitting MS diagnosed between 2008 and 2021 were included. Those without data regarding their education levels were excluded. Binary, multinomial and Cox regression models were used to examine the association between education levels and uptake of DMTs.Results: A total of 6317 participants fulfilled all inclusion and exclusion criteria. A total of 1826/2923 (62%) participants with a university education were treated with DMTs, compared to 1788/3394 (53%) participants with school/diploma received DMTs with an odds ratio of 1.318 (1.178–1.473). Participants with a university education were more likely to be treated with both moderate- and high-efficacy DMTs, compared to others, with odds ratios of 1.227 (1.087–1.385) and 1.545 (1.325–1.802), respectively. University education was also a positive predictor for faster initiation of DMTs, and, importantly, higher-efficacy DMTs.Conclusion: In a publicly funded health care system, despite intended equality of access, university education was associated with a higher uptake of DMTs.
published_date 2024-02-01T13:33:00Z
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score 11.03559

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