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EarLy Exercise in blunt Chest wall Trauma: A multi-centre, parallel randomised controlled trial (ELECT2 Trial)

Ceri Battle, Timothy Driscoll Orcid Logo, Deborah Fitzsimmons Orcid Logo, Shaun Harris Orcid Logo, Fiona Lecky, Claire O'Neill Orcid Logo, Alan Watkins Orcid Logo, Jane Barnett, Susan Davies, Hayley Hutchings Orcid Logo, Kate Jones, Andrew Eglington, Sophie Place, Hannah Toghill, Katie Foster, Bethan Uzzell, Elizabeth Ford, Mark Baker, Sophie Lewis, Sara Davies, Sarah Nicholls, Amy Charnock, Claire Watkins, Sarah-Jane Garside, Jeannie Bishop, Thomas Dawson, Jessica Pendlebury, Reece Doonan

Injury, Start page: 112075

Swansea University Authors: Ceri Battle, Timothy Driscoll Orcid Logo, Deborah Fitzsimmons Orcid Logo, Shaun Harris Orcid Logo, Claire O'Neill Orcid Logo, Alan Watkins Orcid Logo, Hayley Hutchings Orcid Logo

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Abstract

Introduction: The aim of this trial was to investigate the impact of early thoracic and shoulder girdle exercises on chronic pain and Health-Related Quality of Life in patients with blunt chest wall trauma, when compared to normal care. Methods: A multi-centre, parallel, randomised controlled trial,...

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Published in: Injury
ISSN: 0020-1383
Published: Elsevier BV 2024
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa68466
Abstract: Introduction: The aim of this trial was to investigate the impact of early thoracic and shoulder girdle exercises on chronic pain and Health-Related Quality of Life in patients with blunt chest wall trauma, when compared to normal care. Methods: A multi-centre, parallel, randomised controlled trial, in which adult patients presenting to hospital with blunt chest wall trauma were allocated to either control or intervention group. The intervention was an exercise programme consisting of four simple thoracic and shoulder girdle exercises, completed for one week. Outcomes measures included prevalence and severity of chronic pain using the Brief Pain Inventory, health-related quality of life using EQ-5D-5 L, and cost effectiveness, measured at initial presentation and three months post-injury. Results: 360 participants were recruited. Participants’ mean age was 63.6 years (standard deviation (SD): 17.9 years) and 213 (59.8 %) were men. After loss-to-follow-up, the survey response rate at three months was 73.0 % (251/344 participants). The primary analysis, for chronic pain prevalence at three months post-injury, found no statistically significant differences between intervention and control groups, with lower rates in the control (intervention: 35/126 (27.8 %), control: 20/117 (17.1 %); adjusted odds ratio 1.862; 95 % CI: 0.892 to 3.893, p = 0.098). There were no statistically significant differences between intervention and control groups for pain severity at three months post-injury, (intervention mean (SD): 2.15 (2.49), control: 1.81 (2.10); adjusted difference 0.196, 95 % CI:0.340 to 0.731; p = 0.473); or Health-Related Quality of Life (intervention mean (SD): 0.715 (0.291), control: 0.704 (0.265); adjusted difference: 0.030; 95 % CI:0.033 to 0.094; p = 0.350). The health economic analysis found the intervention was associated with higher costs compared to normal care. Conclusion: The results of this trial did not support a ‘one-size fits all’ simple, early exercise programme for patients with blunt chest wall trauma. Future research should consider the impact of a personalised exercise programme, commenced by the patient at least one week post-injury.
Keywords: Blunt chest trauma; Early exercise; Chronic pain; Health-related quality of life
College: Faculty of Medicine, Health and Life Sciences
Funders: This study was supported by Health and Care Research Wales on behalf of Welsh Government (Grant number RfPPB 20-1738).
Start Page: 112075