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Acute Effects of Caffeine and Taurine Co‐Ingestion on Time to Exhaustion and Thermoregulatory Responses to Cycling in the Heat

James Aggett, Joe Page, Jennifer Peel, Kevin John, Guilherme Garcia Matta Orcid Logo, Jamie Tallent, Shane Heffernan Orcid Logo, Owen Jeffries, Mark Waldron Orcid Logo

European Journal of Sport Science, Volume: 25, Issue: 10, Start page: e70044

Swansea University Authors: James Aggett, Joe Page, Jennifer Peel, Guilherme Garcia Matta Orcid Logo, Shane Heffernan Orcid Logo, Mark Waldron Orcid Logo

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DOI (Published version): 10.1002/ejsc.70044

Abstract

Caffeine and taurine are commonly co-ingested pre-exercise but elicit different thermoregulatory responses; however, their combined effect on thermoregulation is unknown. Therefore, we evaluated the effects of oral caffeine and taurine co-ingestion on time to exhaustion (TTE) and thermoregulatory re...

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Published in: European Journal of Sport Science
ISSN: 1746-1391 1536-7290
Published: Wiley 2025
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URI: https://cronfa.swan.ac.uk/Record/cronfa70332
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There were no differences between conditions for skin (p = 0.539) and core temperature (p = 0.699), mean skin blood flow (p = 0.119), respiratory exchange ratio (p = 0.546) and WBSR (p = 0.897). Pre-exercise co-ingestion of caffeine and taurine in the heat had no ergogenic effect despite increasing the ventilatory and metabolic demand. 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spelling 2025-10-22T10:23:28.5751686 v2 70332 2025-09-11 Acute Effects of Caffeine and Taurine Co‐Ingestion on Time to Exhaustion and Thermoregulatory Responses to Cycling in the Heat 7b8371e8cdb64aad32beb3e4ec677b15 James Aggett James Aggett true false dff041586f0621c885755f69eb28eac6 Joe Page Joe Page true false 86316fdeb6b4ee7ce0206f789eec781c Jennifer Peel Jennifer Peel true false 32887edb5bf791c6b557b5be5e197a81 0000-0001-5622-5442 Guilherme Garcia Matta Guilherme Garcia Matta true false 72c0b36891dfbec0378c0d0f7916e807 0000-0002-3297-9335 Shane Heffernan Shane Heffernan true false 70db7c6c54d46f5e70b39e5ae0a056fa 0000-0002-2720-4615 Mark Waldron Mark Waldron true false 2025-09-11 Caffeine and taurine are commonly co-ingested pre-exercise but elicit different thermoregulatory responses; however, their combined effect on thermoregulation is unknown. Therefore, we evaluated the effects of oral caffeine and taurine co-ingestion on time to exhaustion (TTE) and thermoregulatory responses to cycling in the heat at the gas exchange threshold (GET). Ten healthy nonheat acclimated participants took part in a double-blind crossover study, completing a TTE in the heat (35°C; 40% relative humidity), cycling at a power output associated with the GET and 1 h after ingesting: caffeine (5 mg/kg) and taurine (50 mg/kg) combined or placebo. Pulmonary gas exchange, core and mean skin temperatures and whole-body sweat rate (WBSR) were recorded throughout. Heat production was determined using partitional calorimetry. There were no differences in TTE between conditions (p = 0.608); however, the rate of oxygen consumption (p = 0.017), minute ventilation (p = 0.029) and heat production (p = 0.019) were higher following the supplement. There were no differences between conditions for skin (p = 0.539) and core temperature (p = 0.699), mean skin blood flow (p = 0.119), respiratory exchange ratio (p = 0.546) and WBSR (p = 0.897). Pre-exercise co-ingestion of caffeine and taurine in the heat had no ergogenic effect despite increasing the ventilatory and metabolic demand. Collectively, these data indicate minimal effects on whole-body thermoregulation. Journal Article European Journal of Sport Science 25 10 e70044 Wiley 1746-1391 1536-7290 endurance, environmental physiology, exercise, nutrition, performance 1 10 2025 2025-10-01 10.1002/ejsc.70044 COLLEGE NANME COLLEGE CODE Swansea University SU Library paid the OA fee (TA Institutional Deal) Swansea University 2025-10-22T10:23:28.5751686 2025-09-11T11:43:50.0108517 Faculty of Science and Engineering School of Engineering and Applied Sciences - Sport and Exercise Sciences James Aggett 1 Joe Page 2 Jennifer Peel 3 Kevin John 4 Guilherme Garcia Matta 0000-0001-5622-5442 5 Jamie Tallent 6 Shane Heffernan 0000-0002-3297-9335 7 Owen Jeffries 8 Mark Waldron 0000-0002-2720-4615 9 70332__35435__ceba6e750992451f8dd374b2a0608f25.pdf 70332.VOR.pdf 2025-10-22T10:20:04.3993713 Output 1185921 application/pdf Version of Record true © 2025 The Author(s). European Journal of Sport Science published by Wiley-VCH GmbH on behalf of European College of Sport Science. This is an open access article under the terms of the Creative Commons Attribution License (CC BY). true eng http://creativecommons.org/licenses/by/4.0/
title Acute Effects of Caffeine and Taurine Co‐Ingestion on Time to Exhaustion and Thermoregulatory Responses to Cycling in the Heat
spellingShingle Acute Effects of Caffeine and Taurine Co‐Ingestion on Time to Exhaustion and Thermoregulatory Responses to Cycling in the Heat
James Aggett
Joe Page
Jennifer Peel
Guilherme Garcia Matta
Shane Heffernan
Mark Waldron
title_short Acute Effects of Caffeine and Taurine Co‐Ingestion on Time to Exhaustion and Thermoregulatory Responses to Cycling in the Heat
title_full Acute Effects of Caffeine and Taurine Co‐Ingestion on Time to Exhaustion and Thermoregulatory Responses to Cycling in the Heat
title_fullStr Acute Effects of Caffeine and Taurine Co‐Ingestion on Time to Exhaustion and Thermoregulatory Responses to Cycling in the Heat
title_full_unstemmed Acute Effects of Caffeine and Taurine Co‐Ingestion on Time to Exhaustion and Thermoregulatory Responses to Cycling in the Heat
title_sort Acute Effects of Caffeine and Taurine Co‐Ingestion on Time to Exhaustion and Thermoregulatory Responses to Cycling in the Heat
author_id_str_mv 7b8371e8cdb64aad32beb3e4ec677b15
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86316fdeb6b4ee7ce0206f789eec781c
32887edb5bf791c6b557b5be5e197a81
72c0b36891dfbec0378c0d0f7916e807
70db7c6c54d46f5e70b39e5ae0a056fa
author_id_fullname_str_mv 7b8371e8cdb64aad32beb3e4ec677b15_***_James Aggett
dff041586f0621c885755f69eb28eac6_***_Joe Page
86316fdeb6b4ee7ce0206f789eec781c_***_Jennifer Peel
32887edb5bf791c6b557b5be5e197a81_***_Guilherme Garcia Matta
72c0b36891dfbec0378c0d0f7916e807_***_Shane Heffernan
70db7c6c54d46f5e70b39e5ae0a056fa_***_Mark Waldron
author James Aggett
Joe Page
Jennifer Peel
Guilherme Garcia Matta
Shane Heffernan
Mark Waldron
author2 James Aggett
Joe Page
Jennifer Peel
Kevin John
Guilherme Garcia Matta
Jamie Tallent
Shane Heffernan
Owen Jeffries
Mark Waldron
format Journal article
container_title European Journal of Sport Science
container_volume 25
container_issue 10
container_start_page e70044
publishDate 2025
institution Swansea University
issn 1746-1391
1536-7290
doi_str_mv 10.1002/ejsc.70044
publisher Wiley
college_str Faculty of Science and Engineering
hierarchytype
hierarchy_top_id facultyofscienceandengineering
hierarchy_top_title Faculty of Science and Engineering
hierarchy_parent_id facultyofscienceandengineering
hierarchy_parent_title Faculty of Science and Engineering
department_str School of Engineering and Applied Sciences - Sport and Exercise Sciences{{{_:::_}}}Faculty of Science and Engineering{{{_:::_}}}School of Engineering and Applied Sciences - Sport and Exercise Sciences
document_store_str 1
active_str 0
description Caffeine and taurine are commonly co-ingested pre-exercise but elicit different thermoregulatory responses; however, their combined effect on thermoregulation is unknown. Therefore, we evaluated the effects of oral caffeine and taurine co-ingestion on time to exhaustion (TTE) and thermoregulatory responses to cycling in the heat at the gas exchange threshold (GET). Ten healthy nonheat acclimated participants took part in a double-blind crossover study, completing a TTE in the heat (35°C; 40% relative humidity), cycling at a power output associated with the GET and 1 h after ingesting: caffeine (5 mg/kg) and taurine (50 mg/kg) combined or placebo. Pulmonary gas exchange, core and mean skin temperatures and whole-body sweat rate (WBSR) were recorded throughout. Heat production was determined using partitional calorimetry. There were no differences in TTE between conditions (p = 0.608); however, the rate of oxygen consumption (p = 0.017), minute ventilation (p = 0.029) and heat production (p = 0.019) were higher following the supplement. There were no differences between conditions for skin (p = 0.539) and core temperature (p = 0.699), mean skin blood flow (p = 0.119), respiratory exchange ratio (p = 0.546) and WBSR (p = 0.897). Pre-exercise co-ingestion of caffeine and taurine in the heat had no ergogenic effect despite increasing the ventilatory and metabolic demand. Collectively, these data indicate minimal effects on whole-body thermoregulation.
published_date 2025-10-01T08:15:23Z
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