No Cover Image

Journal article 119 views

Validation of the General Practice Physical Activity Questionnaire after severe COVID-19

Lin Wang, Kimon Ntotsis, James Manifield, Katerina Tziannou, Tatiana Plekhanova, Alex Rowlands, Charlotte L. Edwardson, Maxime Taquet, Amisha Singapuri, Annemarie Docherty, Aarti Shikotra, Alexander Horsley, Beatriz Guillen-Guio, Betty Raman, Charlotte Bolton, Claire Nolan, Claudia Efstathiou, Daniel Lozano-Rojas, David J. Stensel, Enya Daynes, Ewen Harrison, Hamish McAuley, Ioannis Vogiatzis, Jack Sargeant, James Chalmers, Jennifer K. Quint, Joseph Jacob, Nicolette C. Bishop, Linzy Houchen-Wolloff, Ling-Pei Ho, Lucy Gardiner, Marco Sereno, Mathew Thorpe, Matthew Richardson, Melitta McNarry Orcid Logo, Michael Marks, Molly Baldwin, Nazir Lone, Neil Greening, Omer Elneima, Olivia Leavy, Ruth M. Saunders, Victoria Harris, William Greenhalf, William Man, Louise V. Wain, Iain Stewart, Sally Singh, Christopher E. Brightling, Claire Lawson, Tom Yates, Rachael A. Evans

ERJ Open Research

Swansea University Author: Melitta McNarry Orcid Logo

Full text not available from this repository: check for access using links below.

Check full text

Abstract

Background: Physical inactivity is a risk factor for severe COVID-19 and often worsens after hospitalisation. Clinicians need quick, accurate assessments to target interventions. We aimed to assess the validity of the General Practice Physical Activity Questionnaire (GPPAQ) in adults recovering one...

Full description

Published in: ERJ Open Research
ISSN: 2312-0541
Published: European Respiratory Society
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa71662
Abstract: Background: Physical inactivity is a risk factor for severe COVID-19 and often worsens after hospitalisation. Clinicians need quick, accurate assessments to target interventions. We aimed to assess the validity of the General Practice Physical Activity Questionnaire (GPPAQ) in adults recovering one year after COVID-19 hospitalisation. Methods: Post-hospitalisation for COVID-19, adults attended a one-year-visit and completed the GPPAQ Physical Activity Index (PAI-4 active), 14-day wrist-worn accelerometry (Moderate-Vigorous PA [MVPA]- active), and other health outcomes. Validity was examined via: (i) internal consistency (factor analysis); (ii) measurement invariance across sex, age, and ethnicity using differential item functioning (DIF); (iii) convergent validity (GPPAQ sensitivity/specificity vs accelerometry); and (iv) construct validity (correlations with health outcomes). Results: 752 participants had GPPAQ and accelerometry (265 female, mean±SD age 60.9±11.6 years, MVPA 18.75 min/day (IQR 7.55, 36.11), PAI-1 46.8%, PAI-2 15.6%, PAI-3 19.4%, PAI-4 18.2%. Factor analyses supported good internal consistency with two factors (daily activities, physical exercise). Confirmatory factor Index(CFI) showed excellent fit (CFI 0.965). DIF indicated moderate variability by sex and age. GPPAQ-PAI showed limited sensitivity (26.3%) for correctly classifying physically active individuals, but higher specificity (88.4%) for classifying physical inactivity, and weak-to-moderate correlations with health outcomes. Conclusions: GPPAQ demonstrates internal consistency, with construct and convergent validity in adults 1-year post-COVID-19 hospitalisation. GPPAQ effectively identifies inactive individuals to support clinical care; however, its sensitivity suggests underestimation of activity relative to accelerometry. Future pathways should combine GPPAQ with device-based assessment to optimise evaluation of physical activity to guide pulmonary rehabilitation and targeted interventions. 
Item Description: In press
College: Faculty of Science and Engineering
Funders: National Institute for Health and Care Research (NIHR) and UK Research and Innovation (UKRI) [PHOSP COVID, grant references: MR/V027859/1 and COV0319].

Similar Items