Assessing the efficacy, safety and utility of fully closed-loop insulin delivery compared to standard insulin therapy with a continuous glucose monitor in adults with type 2 diabetes (COYOTE study): a randomised parallel study protocol

Seese, R; Boughton, CK; Tseung, FT; Uy, R; Wilinska, ME; Thabit, H; Cheah, YS; Neupane, S; Hussain, S; Choudhary, P; Wilmot, EG; Bally, L; Hanaire, H; Mader, JK; Haluzík, M; O’Neal, D; Lawton, J; Rankin, D; Kollman, C; Dunseath, Gareth; Hovorka, R

doi:10.1136/bmjopen-2025-115464

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Assessing the efficacy, safety and utility of fully closed-loop insulin delivery compared to standard insulin therapy with a continuous glucose monitor in adults with type 2 diabetes (COYOTE study): a randomised parallel study pro...

R Seese

, CK Boughton, FT Tseung, R Uy, ME Wilinska, H Thabit, YS Cheah

, S Neupane, S Hussain, P Choudhary, EG Wilmot, L Bally

, H Hanaire, JK Mader

, M Haluzík, D O’Neal

, J Lawton, D Rankin, C Kollman, Gareth Dunseath

, R Hovorka

BMJ Open, Volume: 16, Issue: 5, Start page: e115464

Swansea University Author: Gareth Dunseath

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DOI (Published version): 10.1136/bmjopen-2025-115464

Published in:	BMJ Open
ISSN:	2044-6055 2044-6055
Published:	BMJ 2026
Online Access:	Check full text
URI:	https://cronfa.swan.ac.uk/Record/cronfa72049

first_indexed	2026-06-11T09:31:48Z
last_indexed	2026-06-12T13:21:35Z
id	cronfa72049
recordtype	SURis
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spelling	2026-06-11T10:31:46.9467654 v2 72049 2026-06-11 Assessing the efficacy, safety and utility of fully closed-loop insulin delivery compared to standard insulin therapy with a continuous glucose monitor in adults with type 2 diabetes (COYOTE study): a randomised parallel study protocol fccbba9edcaee08a839a3c5cff8cbe19 0000-0001-6022-862X Gareth Dunseath Gareth Dunseath true false 2026-06-11 MEDS Journal Article BMJ Open 16 5 e115464 BMJ 2044-6055 2044-6055 1 5 2026 2026-05-01 10.1136/bmjopen-2025-115464 https://doi.org/10.1136/bmjopen-2025-115464 COLLEGE NANME Medical School COLLEGE CODE MEDS Swansea University Another institution paid the OA fee 2026-06-11T10:31:46.9467654 2026-06-11T10:29:51.9793085 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Biomedical Science R Seese 0009-0005-0640-0632 1 CK Boughton 2 FT Tseung 3 R Uy 4 ME Wilinska 5 H Thabit 6 YS Cheah 0009-0009-1948-1960 7 S Neupane 8 S Hussain 9 P Choudhary 10 EG Wilmot 11 L Bally 0000-0003-1993-7672 12 H Hanaire 13 JK Mader 0000-0001-7854-4233 14 M Haluzík 15 D O’Neal 0000-0002-0870-4032 16 J Lawton 17 D Rankin 18 C Kollman 19 Gareth Dunseath 0000-0001-6022-862X 20 R Hovorka 21
title	Assessing the efficacy, safety and utility of fully closed-loop insulin delivery compared to standard insulin therapy with a continuous glucose monitor in adults with type 2 diabetes (COYOTE study): a randomised parallel study protocol
spellingShingle	Assessing the efficacy, safety and utility of fully closed-loop insulin delivery compared to standard insulin therapy with a continuous glucose monitor in adults with type 2 diabetes (COYOTE study): a randomised parallel study protocol Gareth Dunseath
title_short	Assessing the efficacy, safety and utility of fully closed-loop insulin delivery compared to standard insulin therapy with a continuous glucose monitor in adults with type 2 diabetes (COYOTE study): a randomised parallel study protocol
title_full	Assessing the efficacy, safety and utility of fully closed-loop insulin delivery compared to standard insulin therapy with a continuous glucose monitor in adults with type 2 diabetes (COYOTE study): a randomised parallel study protocol
title_fullStr	Assessing the efficacy, safety and utility of fully closed-loop insulin delivery compared to standard insulin therapy with a continuous glucose monitor in adults with type 2 diabetes (COYOTE study): a randomised parallel study protocol
title_full_unstemmed	Assessing the efficacy, safety and utility of fully closed-loop insulin delivery compared to standard insulin therapy with a continuous glucose monitor in adults with type 2 diabetes (COYOTE study): a randomised parallel study protocol
title_sort	Assessing the efficacy, safety and utility of fully closed-loop insulin delivery compared to standard insulin therapy with a continuous glucose monitor in adults with type 2 diabetes (COYOTE study): a randomised parallel study protocol
author_id_str_mv	fccbba9edcaee08a839a3c5cff8cbe19
author_id_fullname_str_mv	fccbba9edcaee08a839a3c5cff8cbe19_***_Gareth Dunseath
author	Gareth Dunseath
author2	R Seese CK Boughton FT Tseung R Uy ME Wilinska H Thabit YS Cheah S Neupane S Hussain P Choudhary EG Wilmot L Bally H Hanaire JK Mader M Haluzík D O’Neal J Lawton D Rankin C Kollman Gareth Dunseath R Hovorka
format	Journal article
container_title	BMJ Open
container_volume	16
container_issue	5
container_start_page	e115464
publishDate	2026
institution	Swansea University
issn	2044-6055 2044-6055
doi_str_mv	10.1136/bmjopen-2025-115464
publisher	BMJ
college_str	Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id	facultyofmedicinehealthandlifesciences
hierarchy_top_title	Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id	facultyofmedicinehealthandlifesciences
hierarchy_parent_title	Faculty of Medicine, Health and Life Sciences
department_str	Swansea University Medical School - Biomedical Science{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Biomedical Science
url	https://doi.org/10.1136/bmjopen-2025-115464
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published_date	2026-05-01T06:39:56Z
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Assessing the efficacy, safety and utility of fully closed-loop insulin delivery compared to standard insulin therapy with a continuous glucose monitor in adults with type 2 diabetes (COYOTE study): a randomised parallel study pro...

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