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Procedural and declarative memory task performance, and the memory consolidation function of sleep, in recent and abstinent ecstasy/MDMA users / M Blagrove; J Seddon; S George; A. C Parrott; R Stickgold; M. P Walker; K. A Jones; M. J Morgan

Journal of Psychopharmacology, Volume: 25, Issue: 4, Pages: 465 - 477

Swansea University Author: Blagrove, Mark

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Abstract

This study assessed declarative and procedural memory in ecstasy/MDMA users. Groups were: drug-naive controls (n = 24); recent ecstasy/MDMA users, who had taken ecstasy/MDMA 2–3 days before the first testing session (n = 25), and abstinent users, who had not taken ecstasy/MDMA for at least 8 days be...

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Published in: Journal of Psychopharmacology
ISSN: 0269-8811 1461-7285
Published: 2011
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa9004
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Abstract: This study assessed declarative and procedural memory in ecstasy/MDMA users. Groups were: drug-naive controls (n = 24); recent ecstasy/MDMA users, who had taken ecstasy/MDMA 2–3 days before the first testing session (n = 25), and abstinent users, who had not taken ecstasy/MDMA for at least 8 days before testing (n = 17). Greater lifetime consumption of ecstasy was associated with poorer procedural memory. Recent ecstasy/MDMA users who had taken other drugs (mainly cannabis) 48–24 h before testing exhibited poorer declarative memory than controls. Greater lifetime consumption of ecstasy, and of cocaine, were associated with greater deficits in declarative memory. These results suggest that procedural, as well as declarative, memory deficits are associated with the extent of past ecstasy use. However, ecstasy/MDMA did not affect the memory consolidation function of sleep for either the declarative or the procedural memory task.
Item Description: The study was funded by an award of £100k from the ESRC to M.Blagrove (PI). Itv was a collaboration between Swansea, Harvard Medical School, UC Berkeley and Sussex.
College: College of Human and Health Sciences
Issue: 4
Start Page: 465
End Page: 477