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Predictors of in-hospital mortality for patients admitted with ST-elevation myocardial infarction: a real-world study using the Myocardial Infarction National Audit Project (MINAP) database. / Clive, Weston

Heart, Volume: 94, Issue: 11, Pages: 1407 - 1412

Swansea University Author: Clive, Weston

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Abstract

The objective was to describe factors predicting inpatient mortality for 34 722 patients with ST elevation myocardial infarction (STEMI) admitted to hospitals in England and Wales and entered in the Myocardial Infarction National Audit Project (MINAP) database between 1 January 2003 to 31 March 2005...

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Published in: Heart
ISSN: 1355-6037
Published: Heart 2008
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URI: https://cronfa.swan.ac.uk/Record/cronfa10011
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Abstract: The objective was to describe factors predicting inpatient mortality for 34 722 patients with ST elevation myocardial infarction (STEMI) admitted to hospitals in England and Wales and entered in the Myocardial Infarction National Audit Project (MINAP) database between 1 January 2003 to 31 March 2005. Analysis included multivariate logistic regression and area under the receiver operating curve analysis.Inpatient mortality was 10.6%. The strongest predictors (highest odds ratios) for inpatient survival were early aspirin therapy and out-of-hospital thrombolysis. A 10-year increase in age was associated with a doubling of inpatient mortality risk, whereas cerebrovascular disease increased it by 1.7. The derived risk model comprised 14 predictors of mortality with a C index  =  0.82 (95% CI 0.82 to 0.83, p<0.001); while a simplified model comprising age, systolic blood pressure (SBP) and heart rate (HR) offered a C index of 0.80 (0.79 to 0.80, p<0.001).
College: Swansea University Medical School
Issue: 11
Start Page: 1407
End Page: 1412