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Predictors of in-hospital mortality for patients admitted with ST-elevation myocardial infarction: a real-world study using the Myocardial Infarction National Audit Project (MINAP) database.

CP Gale, SOM Manda, PD Batin, CF Weston, J Birkhead, A Hall, Clive Weston Orcid Logo

Heart, Volume: 94, Issue: 11, Pages: 1407 - 1412

Swansea University Author: Clive Weston Orcid Logo

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DOI (Published version): 10.1136/hrt.2007.127068

Abstract

The objective was to describe factors predicting inpatient mortality for 34 722 patients with ST elevation myocardial infarction (STEMI) admitted to hospitals in England and Wales and entered in the Myocardial Infarction National Audit Project (MINAP) database between 1 January 2003 to 31 March 2005...

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Published in: Heart
ISSN: 1355-6037
Published: Heart 2008
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URI: https://cronfa.swan.ac.uk/Record/cronfa10011
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first_indexed 2013-07-23T12:02:37Z
last_indexed 2018-02-09T04:38:33Z
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spelling 2013-11-08T11:20:57.3366074 v2 10011 2012-03-21 Predictors of in-hospital mortality for patients admitted with ST-elevation myocardial infarction: a real-world study using the Myocardial Infarction National Audit Project (MINAP) database. df85e4e0e139d0f46eb683174eba98a9 0000-0002-8995-8199 Clive Weston Clive Weston true false 2012-03-21 PMSC The objective was to describe factors predicting inpatient mortality for 34 722 patients with ST elevation myocardial infarction (STEMI) admitted to hospitals in England and Wales and entered in the Myocardial Infarction National Audit Project (MINAP) database between 1 January 2003 to 31 March 2005. Analysis included multivariate logistic regression and area under the receiver operating curve analysis.Inpatient mortality was 10.6%. The strongest predictors (highest odds ratios) for inpatient survival were early aspirin therapy and out-of-hospital thrombolysis. A 10-year increase in age was associated with a doubling of inpatient mortality risk, whereas cerebrovascular disease increased it by 1.7. The derived risk model comprised 14 predictors of mortality with a C index  =  0.82 (95% CI 0.82 to 0.83, p<0.001); while a simplified model comprising age, systolic blood pressure (SBP) and heart rate (HR) offered a C index of 0.80 (0.79 to 0.80, p<0.001). Journal Article Heart 94 11 1407 1412 Heart 1355-6037 31 12 2008 2008-12-31 10.1136/hrt.2007.127068 COLLEGE NANME Medicine COLLEGE CODE PMSC Swansea University 2013-11-08T11:20:57.3366074 2012-03-21T16:17:18.0000000 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine CP Gale 1 SOM Manda 2 PD Batin 3 CF Weston 4 J Birkhead 5 A Hall 6 Clive Weston 0000-0002-8995-8199 7
title Predictors of in-hospital mortality for patients admitted with ST-elevation myocardial infarction: a real-world study using the Myocardial Infarction National Audit Project (MINAP) database.
spellingShingle Predictors of in-hospital mortality for patients admitted with ST-elevation myocardial infarction: a real-world study using the Myocardial Infarction National Audit Project (MINAP) database.
Clive Weston
title_short Predictors of in-hospital mortality for patients admitted with ST-elevation myocardial infarction: a real-world study using the Myocardial Infarction National Audit Project (MINAP) database.
title_full Predictors of in-hospital mortality for patients admitted with ST-elevation myocardial infarction: a real-world study using the Myocardial Infarction National Audit Project (MINAP) database.
title_fullStr Predictors of in-hospital mortality for patients admitted with ST-elevation myocardial infarction: a real-world study using the Myocardial Infarction National Audit Project (MINAP) database.
title_full_unstemmed Predictors of in-hospital mortality for patients admitted with ST-elevation myocardial infarction: a real-world study using the Myocardial Infarction National Audit Project (MINAP) database.
title_sort Predictors of in-hospital mortality for patients admitted with ST-elevation myocardial infarction: a real-world study using the Myocardial Infarction National Audit Project (MINAP) database.
author_id_str_mv df85e4e0e139d0f46eb683174eba98a9
author_id_fullname_str_mv df85e4e0e139d0f46eb683174eba98a9_***_Clive Weston
author Clive Weston
author2 CP Gale
SOM Manda
PD Batin
CF Weston
J Birkhead
A Hall
Clive Weston
format Journal article
container_title Heart
container_volume 94
container_issue 11
container_start_page 1407
publishDate 2008
institution Swansea University
issn 1355-6037
doi_str_mv 10.1136/hrt.2007.127068
publisher Heart
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Medicine{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medicine
document_store_str 0
active_str 0
description The objective was to describe factors predicting inpatient mortality for 34 722 patients with ST elevation myocardial infarction (STEMI) admitted to hospitals in England and Wales and entered in the Myocardial Infarction National Audit Project (MINAP) database between 1 January 2003 to 31 March 2005. Analysis included multivariate logistic regression and area under the receiver operating curve analysis.Inpatient mortality was 10.6%. The strongest predictors (highest odds ratios) for inpatient survival were early aspirin therapy and out-of-hospital thrombolysis. A 10-year increase in age was associated with a doubling of inpatient mortality risk, whereas cerebrovascular disease increased it by 1.7. The derived risk model comprised 14 predictors of mortality with a C index  =  0.82 (95% CI 0.82 to 0.83, p<0.001); while a simplified model comprising age, systolic blood pressure (SBP) and heart rate (HR) offered a C index of 0.80 (0.79 to 0.80, p<0.001).
published_date 2008-12-31T03:10:37Z
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score 11.036706

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