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Mammalian Cell HPRT Gene Mutation Assay: Test Methods
Methods in Molecular Biology, Volume: 817, Pages: 55 - 67
Swansea University Author: George Johnson
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DOI (Published version): 10.1007/978-1-61779-421-6_4
Abstract
Mammalian Cell HPRT Gene Mutation Assay: Test Methods
Published in: | Methods in Molecular Biology |
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ISBN: | 978-1-61779-420-9 978-1-61779-421-6 |
ISSN: | 1064-3745 1940-6029 |
Published: |
New York
Springer
2012
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Online Access: |
Check full text
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URI: | https://cronfa.swan.ac.uk/Record/cronfa10435 |
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Item Description: |
This chapter has become the standard operating procedure for EU laboratories to carry our the HPRT assay for submission to the European Chemicals Agency under REACH. This is leading to citations (2 since January 2012), and 125 chapter sales in the last 90 days at 40 Euro each. It will have high impact for REACH and laboratories to carry out this necessary experiment when carrying out hazard and risk assessment on the 40,000 or so chemicals submitted to REACH. http://www.springer.com/biomed/pharmaceutical+science/book/978-1-61779-420-9 |
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Keywords: |
HPRT gene mutation; Human cells; Mammalian cell mutation; Mutation testing |
College: |
Faculty of Medicine, Health and Life Sciences |
Start Page: |
55 |
End Page: |
67 |