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Influence of DNA Repair on Nonlinear Dose-Responses for Mutation / A. D Thomas; G. J. S Jenkins; B Kaina; O. G Bodger; K.-H Tomaszowski; P. D Lewis; S. H Doak; G. E Johnson; Gareth Jenkins; Paul Lewis; Shareen Doak; Owen Bodger; George Johnson

Toxicological Sciences, Volume: 132, Issue: 1, Pages: 87 - 95

Swansea University Authors: Gareth, Jenkins, Paul, Lewis, Shareen, Doak, Owen, Bodger, George, Johnson

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DOI (Published version): 10.1093/toxsci/kfs341

Published in: Toxicological Sciences
ISSN: 1096-6080 1096-0929
Published: 2013
Online Access: Check full text

URI: https://cronfa.swan.ac.uk/Record/cronfa13715
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Item Description: This is a high impact paper that supports our impact story on thresholds. It is the key that many scientists and regulators are waiting for to carry out their hazard and risk assessments, as it shows the mechanism for non-linear dose responses which is a requirement for this process that is currently unavailable to them.
Keywords: alkylating agents, Agents, DNA repair, Genetic Toxicology, dose- response, Risk Assessment, DNA adducts, genotoxicity, mutagen
College: Swansea University Medical School
Issue: 1
Start Page: 87
End Page: 95