Influence of DNA Repair on Nonlinear Dose-Responses for Mutation

Thomas, A. D; S, G. J.; Kaina, B; Bodger, O. G; Tomaszowski, K.-H; Lewis, P. D; Doak, S. H; Johnson, G. E; Jenkins, Gareth; Lewis, Paul; Doak, Shareen; Bodger, Owen; Johnson, George

doi:10.1093/toxsci/kfs341

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Influence of DNA Repair on Nonlinear Dose-Responses for Mutation

A. D Thomas, G. J. S Jenkins, B Kaina, O. G Bodger, K.-H Tomaszowski, P. D Lewis, S. H Doak, G. E Johnson, Gareth Jenkins

, Paul Lewis, Shareen Doak

, Owen Bodger

, George Johnson

Toxicological Sciences, Volume: 132, Issue: 1, Pages: 87 - 95

Swansea University Authors: Gareth Jenkins , Paul Lewis, Shareen Doak , Owen Bodger , George Johnson

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DOI (Published version): 10.1093/toxsci/kfs341

Published in:	Toxicological Sciences
ISSN:	1096-6080 1096-0929
Published:	2013
Online Access:	Check full text
URI:	https://cronfa.swan.ac.uk/Record/cronfa13715

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last_indexed	2019-06-24T19:16:46Z
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spelling	2019-06-24T14:32:14.5455925 v2 13715 2012-12-17 Influence of DNA Repair on Nonlinear Dose-Responses for Mutation a44095d26187304e903da7ca778697b6 0000-0002-5437-8389 Gareth Jenkins Gareth Jenkins true false 46dfc22d7468f247c390ba0c6cd8fba6 Paul Lewis Paul Lewis true false 8f70286908f67238a527a98cbf66d387 0000-0002-6753-1987 Shareen Doak Shareen Doak true false 8096440ab42b60a86e6aba678fe2695a 0000-0002-4022-9964 Owen Bodger Owen Bodger true false 37d0f121db69fd09f364df89e4405e31 0000-0001-5643-9942 George Johnson George Johnson true false 2012-12-17 MEDS Journal Article Toxicological Sciences 132 1 87 95 1096-6080 1096-0929 alkylating agents, Agents, DNA repair, Genetic Toxicology, dose- response, Risk Assessment, DNA adducts, genotoxicity, mutagen 31 3 2013 2013-03-31 10.1093/toxsci/kfs341 This is a high impact paper that supports our impact story on thresholds. It is the key that many scientists and regulators are waiting for to carry out their hazard and risk assessments, as it shows the mechanism for non-linear dose responses which is a requirement for this process that is currently unavailable to them. COLLEGE NANME Medical School COLLEGE CODE MEDS Swansea University 2019-06-24T14:32:14.5455925 2012-12-17T09:19:07.0364997 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medicine A. D Thomas 1 G. J. S Jenkins 2 B Kaina 3 O. G Bodger 4 K.-H Tomaszowski 5 P. D Lewis 6 S. H Doak 7 G. E Johnson 8 Gareth Jenkins 0000-0002-5437-8389 9 Paul Lewis 10 Shareen Doak 0000-0002-6753-1987 11 Owen Bodger 0000-0002-4022-9964 12 George Johnson 0000-0001-5643-9942 13 0013715-28112014091018.pdf 2013__Thomas__et__al.pdf 2014-11-28T09:10:18.6470000 Output 1518396 application/pdf Version of Record true 2014-11-28T00:00:00.0000000 Distributed under the terms of a Creative Commons Attribution (CC-BY-4.0) true
title	Influence of DNA Repair on Nonlinear Dose-Responses for Mutation
spellingShingle	Influence of DNA Repair on Nonlinear Dose-Responses for Mutation Gareth Jenkins Paul Lewis Shareen Doak Owen Bodger George Johnson
title_short	Influence of DNA Repair on Nonlinear Dose-Responses for Mutation
title_full	Influence of DNA Repair on Nonlinear Dose-Responses for Mutation
title_fullStr	Influence of DNA Repair on Nonlinear Dose-Responses for Mutation
title_full_unstemmed	Influence of DNA Repair on Nonlinear Dose-Responses for Mutation
title_sort	Influence of DNA Repair on Nonlinear Dose-Responses for Mutation
author_id_str_mv	a44095d26187304e903da7ca778697b6 46dfc22d7468f247c390ba0c6cd8fba6 8f70286908f67238a527a98cbf66d387 8096440ab42b60a86e6aba678fe2695a 37d0f121db69fd09f364df89e4405e31
author_id_fullname_str_mv	a44095d26187304e903da7ca778697b6_*_Gareth Jenkins 46dfc22d7468f247c390ba0c6cd8fba6__Paul Lewis 8f70286908f67238a527a98cbf66d387__Shareen Doak 8096440ab42b60a86e6aba678fe2695a__Owen Bodger 37d0f121db69fd09f364df89e4405e31_**_George Johnson
author	Gareth Jenkins Paul Lewis Shareen Doak Owen Bodger George Johnson
author2	A. D Thomas G. J. S Jenkins B Kaina O. G Bodger K.-H Tomaszowski P. D Lewis S. H Doak G. E Johnson Gareth Jenkins Paul Lewis Shareen Doak Owen Bodger George Johnson
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container_volume	132
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container_start_page	87
publishDate	2013
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issn	1096-6080 1096-0929
doi_str_mv	10.1093/toxsci/kfs341
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Influence of DNA Repair on Nonlinear Dose-Responses for Mutation

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