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Ghrelin inhibits LPS-induced release of IL-6 from mouse dopaminergic neurones / Amy L Beynon; M Rowan Brown; Rhiannon Wright; Mark Rees; I Martin Sheldon; Jeffrey Davies; Rowan Brown; Martin Sheldon
Journal of Neuroinflammation, Volume: 10, Issue: 1, Start page: 40
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Ghrelin inhibits LPS-induced release of IL-6 from mouse dopaminergic neurones
|Published in:||Journal of Neuroinflammation|
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This paper illustrates how engineering derived principles can be used to examine high-throughput imaged data and permit both biological quantification and insight into mechanisms that regulate the onset and potential treatment of neuronal disease. Specifically, the paper verifies the anti-inflammatory effect of the regulating hormone, ghrelin, on nerve cells that are damaged in Parkinson's disease and furthermore identifies therapeutic targets for treatment and future protection of Parkinson’s disease.
College of Engineering