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The MIT Domain of UBPY Constitutes a CHMP Binding and Endosomal Localization Signal Required for Efficient Epidermal Growth Factor Receptor Degradation

P. E Row, H Liu, S Hayes, R Welchman, P Charalabous, K Hofmann, M. J Clague, C. M Sanderson, S Urbe, Paula Row

Journal of Biological Chemistry, Volume: 282, Issue: 42, Pages: 30929 - 30937

Swansea University Author: Paula Row

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DOI (Published version): 10.1074/jbc.M704009200

Published in: Journal of Biological Chemistry
ISSN: 0021-9258 1083-351X
Published: 2007
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Item Description: Row cloned the GFP-UBPY constructs, taught Hayes how to do the co-immunoprecipitation experiment, designed and performed the experiment that showed that UBPY lacking the MIT domain was functionally inactive, performed the experiment to localise UBPY delta MIT, and contributed to writing the manuscript.
College: Faculty of Medicine, Health and Life Sciences
Issue: 42
Start Page: 30929
End Page: 30937